Evidence map›Paper›PMID 33488712›Full record

ArticleJournal of oncology2021

LMTK2 as Potential Biomarker for Stratification between Clinically Insignificant and Clinically Significant Prostate Cancer.

Alvydas Vezelis, Julija Simiene, Daiva Dabkeviciene, Marius Kincius, Albertas Ulys, Kestutis Suziedelis, Sonata Jarmalaite, Feliksas Jankevicius

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. CAP superfamily proteins in human: a new target for cancer therapy.Medical oncology (Northwood, London, England) · 2024
    Review
  3. Therapeutic advances of targeting receptor tyrosine kinases in cancer.Signal transduction and targeted therapy · 2024
    Review
  4. Lemur Tyrosine Kinases and Prostate Cancer: A Literature Review.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alvydas VezelisNational Cancer Institute, Santariskiu Street 1, Vilnius, LT 08660, Lithuania.ORCID https://orcid.org/0000-0002-8811-5165
Julija SimieneNational Cancer Institute, Santariskiu Street 1, Vilnius, LT 08660, Lithuania.ORCID https://orcid.org/0000-0001-9358-8859
Daiva DabkevicieneNational Cancer Institute, Santariskiu Street 1, Vilnius, LT 08660, Lithuania.
Marius KinciusNational Cancer Institute, Santariskiu Street 1, Vilnius, LT 08660, Lithuania.
Albertas UlysNational Cancer Institute, Santariskiu Street 1, Vilnius, LT 08660, Lithuania.
Kestutis SuziedelisNational Cancer Institute, Santariskiu Street 1, Vilnius, LT 08660, Lithuania.
Sonata JarmalaiteNational Cancer Institute, Santariskiu Street 1, Vilnius, LT 08660, Lithuania.
Feliksas JankeviciusNational Cancer Institute, Santariskiu Street 1, Vilnius, LT 08660, Lithuania.
National Cancer Institute · LTVilnius University · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A set of prostate tumors tend to grow slowly and do not require active treatment. Therefore, stratification between patients with clinically significant and clinically insignificant prostate cancer (PC) remains a vital issue to avoid overtreatment. Fast development of genetic technologies accelerated development of next-generation molecular tools for reliable PC diagnosis. The aim of this study is to evaluate the diagnostic value of molecular biomarkers (CRISP3, LMTK2, and MSMB) for separation of PC cases from benign prostatic changes and more specifically for identification of clinically significant PC from all pool of PC cases in patients with rising PSA levels. Patients (

Identifiers

PMID33488712
PMCPMC7803409
OpenAlexW3121036227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.