Evidence map›Paper›PMID 33488692›Full record

ArticleNeural plasticity2020

EEG Correlates of Central Origin of Cancer-Related Fatigue.

Didier Allexandre, Dilara Seyidova-Khoshknabi, Mellar P Davis, Vinoth K Ranganathan, Vlodek Siemionow, Declan Walsh, Guang H Yue

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Why do patients with cancer die?Nature reviews. Cancer · 2024
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Didier AllexandreCenter for Mobility and Rehabilitation Engineering Research, Kessler Foundation, West Orange, NJ, USA.ORCID 0000-0002-0178-0956
Dilara Seyidova-KhoshknabiThe Harry R. Horvitz Center for Palliative Medicine, The Taussig Cancer Center, The Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0002-0250-7687
Mellar P DavisThe Harry R. Horvitz Center for Palliative Medicine, The Taussig Cancer Center, The Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0002-7903-3993
Vinoth K RanganathanDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Vlodek SiemionowDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Declan WalshThe Harry R. Horvitz Center for Palliative Medicine, The Taussig Cancer Center, The Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0002-9310-1729
Guang H YueCenter for Mobility and Rehabilitation Engineering Research, Kessler Foundation, West Orange, NJ, USA.ORCID 0000-0002-9516-2410
Cleveland Clinic Lerner College of Medicine · USRutgers, The State University of New Jersey · USCleveland Clinic · USGeisinger Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

Neurophysiological Evaluation of Training Effect on Cancer-Related WeaknessR01CA189665 · NCI · KESSLER FOUNDATION, INC. · PI YUE, GUANG H · 2014 to 2019
$2.0M
NCI NIH HHS R01 CA189665
6 · The paper itself

Abstract

The neurophysiological mechanism of cancer-related fatigue (CRF) remains poorly understood. EEG was examined during a sustained submaximal contraction (SC) task to further understand our prior research findings of greater central contribution to early fatigue during SC in CRF. Advanced cancer patients and matched healthy controls performed an elbow flexor SC until task failure while undergoing neuromuscular testing and EEG recording. EEG power changes over left and right sensorimotor cortices were analyzed and correlated with brief fatigue inventory (BFI) score and evoked muscle force, a measure of central fatigue. Brain electrical activity changes during the SC differed in CRF from healthy subjects mainly in the

Indexed as

AgedElectroencephalographyFatigueFemaleHand StrengthHumansMaleMiddle AgedNeoplasms

Identifiers

PMID33488692
PMCPMC7787808
OpenAlexW3112427174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.