Evidence map›Paper›PMID 33488616›Full record

ArticleFrontiers in immunology2020

Activated Platelets Convert CD14

Su Jeong Lee, Bo Ruem Yoon, Hee Young Kim, Su-Jin Yoo, Seong Wook Kang, Won-Woo Lee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Host-pathogen-immune interactions in an air-liquid interface airway model.Frontiers in cellular and infection microbiology · 2026
    Article
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  12. Article
  13. Article
  14. Thrombocytopenia in Sepsis.Life (Basel, Switzerland) · 2025
    Review
  15. Platelet-Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Su Jeong LeeLaboratory of Autoimmunity and Inflammation (LAI), Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.
Bo Ruem YoonDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Hee Young KimDepartment of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Su-Jin YooDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, South Korea.
Seong Wook KangDepartment of Internal Medicine, Chungnam National University School of Medicine, Daejeon, South Korea.
Won-Woo LeeLaboratory of Autoimmunity and Inflammation (LAI), Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.
Seoul National University · KRChungnam National University · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monocytes are important cellular effectors of innate immune defense. Human monocytes are heterogeneous and can be classified into three distinct subsets based on CD14 and CD16 expression. The expansion of intermediate CD14

Indexed as

PhagocytosisPlatelet ActivationAgedAntigens, CDAntigens, Differentiation, MyelomonocyticArthritis, RheumatoidBlood PlateletsCase-Control StudiesCD163 AntigenCells, Culturedc-Mer Tyrosine KinaseCytokinesFemaleGene Expression RegulationGPI-Linked ProteinsHumansAntigens, CDAntigens, Differentiation, MyelomonocyticCD14 protein, humanCD163 Antigenc-Mer Tyrosine KinaseCytokinesFCGR3B protein, humanGPI-Linked ProteinsLipopolysaccharide ReceptorsMERTK protein, humanP-SelectinReceptors, Cell SurfaceReceptors, IgGSELP protein, humanCD14+CD16+ monocytesIL-6M2 macrophagesMerTKphagocytosisplateletrheumatoid arthritisTGF-β

Identifiers

PMID33488616
PMCPMC7817612
OpenAlexW3118841852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.