Trial reportFrontiers in immunology2020
Geographical Distribution, Incidence, Malignancies, and Outcome of 136 Eastern Slavic Patients With Nijmegen Breakage Syndrome and
Open access · goldAbstract readClinical TrialMulticenter Study
In one paragraph
Trial report in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 40 citations in OpenAlex.
- Germ line genetic NBN variation and predisposition to B-cell acute lymphoblastic leukemia in children.Blood · 2024Trial
- Clinical Impact of Germline Multigene Sequencing in Pediatric Cohorts with a Wide Spectrum of Neoplasms.International journal of molecular sciences · 2026Article
- Inborn errors of immunity with DNA repair disorders: at the interface of immune deficiency, immune dysregulation, and malignancy.Frontiers in immunology · 2026Review
- NovelFrontiers in endocrinology · 2026Article
- First 2-year experience of nationwide newborn screening for severe forms of T and B cell immunodeficiency: 2.3 million newborns analyzed using TREC and KREC in Russia.Frontiers in immunology · 2026Article
- Review
- Review
- Subsequent primary and secondary neoplasms in childhood cancer survivors.Polish journal of radiology · 2025Article
- Update on Recommendations for Cancer Screening and Surveillance in Children with Genomic Instability Disorders.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024Review
- The Spectrum of Disease-Associated Alleles in Countries with a Predominantly Slavic Population.International journal of molecular sciences · 2024Review
- Infant with diffuse large B-cell lymphoma identified postmortem with homozygous founder SlavicFrontiers in pediatrics · 2024Article
- Nijmegen breakage syndrome: 25-year experience of diagnosis and treatment in Ukraine.Frontiers in immunology · 2024Article
- Bone Marrow Failure and Immunodeficiency Associated with Human RAD50 Variants.Journal of clinical immunology · 2023Article
- The NBN founder mutation-Evidence for a country specific difference in age at cancer manifestation.Cancer reports (Hoboken, N.J.) · 2023Article
- TREC/KREC Newborn Screening followed by Next-Generation Sequencing for Severe Combined Immunodeficiency in Japan.Journal of clinical immunology · 2022Article
- Inborn errors of immunity caused by defects in the DNA damage response pathways: Importance of minimizing treatment-related genotoxicity.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022Review
- Newborn screening for severe combined immunodeficiency: The results of the first pilot TREC and KREC study in Ukraine with involving of 10,350 neonates.Frontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
34 authors at 16 institutions in 5 countries.
Svetlana O SharapovaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Olga E PashchenkoImmunology Department, Pirogov Russian National Research Medical University, Moscow, Russia.
Anastasiia V BondarenkoDepartment of Pediatric Infectious Diseases and Pediatric Immunology, Shupyk National Medical Academy of Postgraduate Education, Kiev, Ukraine.
Svetlana S VakhlyarskayaClinical Immunology and Rheumatology Department, Russian Children's Clinical Hospital of Pirogov Russian National Research Medical University, Moscow, Russia.
Tatjana ProkofjevaPediatric Clinic, Children's Clinical University Hospital, Riga, Latvia.
Alina S FedorovaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Ihor SavchakPediatric Department, West-Ukrainian Specialized Children's Medical Center, Lviv, Ukraine.
Yuliya MareikaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Timur T ValievChemotherapy Hemoblastoses Department, Pediatric Oncology and Hematology Research Institute of N.N. Blokhin National Cancer Research Center of the Ministry of Health of Russian Federation, Moscow, Russia.
Alexander PopaPropedevtica of Childhood Diseases Faculty, Pirogov Russian National Research Medical University, Moscow, Russia.
Irina A TuzankinaInstitute of Immunology and Physiology of the Branch of the Russian Academy of Sciences, Federal State Autonomous Educational Intuition of Higher Professional Education (Ural Federal University of a Name of the First President of Russia, B.N. Yeltsin), Yekaterinburg, Russia.
Elena V VlasovaClinical Department, Regional Children's Clinical Hospital №1, Yekaterinburg, Russia.
Inga S SakovichResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Ekaterina A PolyakovaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Natalia V RumiantsevaResearch Department, Republican Medical Center (Mother and Child), Minsk, Belarus.
Irina V NaumchikResearch Department, Republican Medical Center (Mother and Child), Minsk, Belarus.
Svetlana A KulyovaPediatric Oncology Department, N.N. Petrov National Medical Research Center of Oncology, St-Petersburg, Russia.
Svetlana N AleshkevichResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Elena I GolovatayaResearch Department, Republican Medical Center (Mother and Child), Minsk, Belarus.
Nina V MinakovskayaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Mikhail V BelevtsevResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Elena A LatyshevaImmunopathology Department, NRC Institute of Immunology FMBA, Moscow, Russia.
Tatiana V LatyshevaImmunopathology Department, NRC Institute of Immunology FMBA, Moscow, Russia.
Alexander G BeznoshchenkoDepartment of Pediatric Oncology/Hematology, Regional Children's Hospital, Ryazan, Russia.
Hayane AkopyanInstitute of Hereditary Pathology of National Academy of Medical Sciences of Ukraine, Lviv, Ukraine.
Halyna MakukhInstitute of Hereditary Pathology of National Academy of Medical Sciences of Ukraine, Lviv, Ukraine.
Olena KozlovaWest-Ukrainian Specialized Children's Medical Center, Lviv, Ukraine.
Dzmitry S VarabyouDepartment of Ecologic Geography, Belarusian State University, Minsk, Belarus.
Mark BallowDepartment of Pediatrics, University of South Florida at Johns Hopkins All Children's Hospital, Saint Petersburg, FL, United States.
Mei-Sing OngDepartment of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care, Boston, MA, United States.
Jolan E WalterDepartment Pediatric Allergy/Immunology, University of South Florida at Johns Hopkins All Children's Hospital, Saint Petersburg, FL, United States.
Irina V KondratenkoClinical Immunology and Rheumatology Department, Russian Children's Clinical Hospital of Pirogov Russian National Research Medical University, Moscow, Russia.
Larysa V KostyuchenkoPediatric Department, West-Ukrainian Specialized Children's Medical Center, Lviv, Ukraine.
Olga V AleinikovaResearch Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Belarusian Research Center For Pediatric Oncology and Hematology · BYLviv City Children's Hospital · UAPirogov Russian National Research Medical University · RURSPC MT · BYInstitute of Immunology and Physiology · RUNational Academy of Medical Sciences of Ukraine · UARegional Children's Clinical Hospital No. 1 · RUBelarusian State University · BYChildren's Clinical University Hospital · LVHarvard Pilgrim Health Care · USJohns Hopkins All Children's Hospital · USMinistry of Health of the Russian Federation · RURussian Children's Clinical Hospital · RUShupyk National Healthcare University of Ukraine · UAUniversity of South Florida · USUral Federal University · RU
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nijmegen breakage syndrome (NBS) is a DNA repair disorder characterized by combined immunodeficiency and a high predisposition to lymphoid malignancies. The majority of NBS patients are identified with a homozygous five base pair deletion in the
Indexed as
Cell Cycle ProteinsFounder EffectHematologic NeoplasmsLymphoproliferative DisordersNijmegen Breakage SyndromeNuclear ProteinsAdolescentAdultChildChild, PreschoolEurope, EasternFemaleFollow-Up StudiesHumansIncidenceMaleCell Cycle ProteinsNBN protein, humanNuclear Proteinsfounder variantsgeographical locationincidence in East Slavslymphomas, risk of malignanciesNijmegen breakage syndrome (NBS)quality of lifesocial adaptation
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.