ArticleFrontiers in physiology2020
Nitric Oxide and Oxidative Stress Changes at Depth in Breath-Hold Diving.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- Return to an extreme environment exposure after pulmonary infection: SCUBA diving as a model?Physiological reports · 2026Article
- Advances in breath-hold diving research: a state-of-the-art review.European journal of applied physiology · 2026Review
- Psychophysical stress during a 24 h dive: A case study of an older male diver.Physiological reports · 2026Article
- Article
- Sleep Deprivation-Induced Oxidative Stress in Rat Models: A Scoping Systematic Review.Antioxidants (Basel, Switzerland) · 2023Article
- Comparison between Arterial Blood Gases and Oxygen Reserve Index™ in a SCUBA Diver: A Case Report.Healthcare (Basel, Switzerland) · 2023Article
- The "ON-OFF" Switching Response of Reactive Oxygen Species in Acute Normobaric Hypoxia: Preliminary Outcome.International journal of molecular sciences · 2023Article
- Seasonal Oxy-Inflammation and Hydration Status in Non-Elite Freeskiing Racer: A Pilot Study by Non-Invasive Analytic Method.International journal of environmental research and public health · 2023Article
- Enhanced-Precision Measurement of Glutathionyl Hemoglobin by MALDI-ToF MS.Molecules (Basel, Switzerland) · 2023Article
- Serum Amino Acid Profile Changes After Repetitive Breath-Hold Dives: A Preliminary Study.Sports medicine - open · 2022Article
- On the Role of Dietary Nitrate in the Maintenance of Systemic and Oral Health.Dentistry journal · 2022Review
- High-Throughput Griess Assay of Nitrite and Nitrate in Plasma and Red Blood Cells for Human Physiology Studies under Extreme Conditions.Molecules (Basel, Switzerland) · 2021Article
- Endothelial Nitric Oxide Production and Antioxidant Response in Breath-Hold Diving: Genetic Predisposition or Environment Related?Frontiers in physiology · 2021Article
- Effect of Apnea-Induced Hypoxia on Cardiovascular Adaptation and Circulating Biomarkers of Oxidative Stress in Elite Breath-Hold Divers.Frontiers in physiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral mechanisms allow humans to resist the extreme conditions encountered during breath-hold diving. Available nitric oxide (NO) is one of the major contributors to such complex adaptations at depth and oxidative stress is one of the major collateral effects of diving. Due to technical difficulties, these biomarkers have not so far been studied MATERIALS AND
methodsBlood plasma, obtained from 14 expert breath-hold divers, was tested for differences in NOx, TAC, and TBARS between pre-dive, bottom, surface, 30 and 60 min post-dive samples.
resultsWe observed a statistically significant increase of NOx plasma concentration in the "bottom blood draw" as compared to the pre-dive condition while we did not find any difference in the following samples We found a statistically significant decrease in TAC at the bottom but the value returned to normality immediately after reaching the surface. We did not find any statistically significant difference in TBARS. DISCUSSION: The increased plasma NOx values found at the bottom were not observed at surface and post dive sampling (T0, T30, T60), showing a very rapid return to the pre-dive values. Also TAC values returned to pre- diving levels immediately after the end of hyperbaric exposure, probably as a consequence of the activation of endogenous antioxidant defenses. TBARS did not show any difference during the protocol.
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