Evidence map›Paper›PMID 33488288›Full record

ArticleReproductive medicine and biology2021

Maca extracts and estrogen replacement therapy in ovariectomized rats exposed at high altitude.

Roberto O Ybañez-Julca, Daniel Asunción-Alvarez, Javier Palacios, Chukwuemeka R Nwokocha

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Roberto O Ybañez-JulcaLaboratorio de Farmacología Facultad de Farmacia y Bioquímica Universidad Nacional de Trujillo Trujillo Perú.ORCID https://orcid.org/0000-0003-0011-7957
Daniel Asunción-AlvarezLaboratorio de Farmacología Facultad de Farmacia y Bioquímica Universidad Nacional de Trujillo Trujillo Perú.ORCID https://orcid.org/0000-0001-7498-2121
Javier PalaciosLaboratorio de Bioquímica Aplicada Facultad de Ciencias de la Salud Universidad Arturo Prat Iquique Chile.ORCID https://orcid.org/0000-0002-7997-9295
Chukwuemeka R NwokochaDepartment of Basic Medical Sciences Faculty of Medical Sciences The University of the West Indies Kingston Jamaica.ORCID https://orcid.org/0000-0001-7092-9382
National University of Trujillo · PEArturo Prat University · CLUniversity of the West Indies System · JM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHormone Replacement Therapy (HRT) and herbal remedies are often used to alleviate menopausal symptoms, but their effects and efficacy at high altitudes presents with several uncertainties. The purpose of this study was to evaluate whether pre-treatment with maca (

methodThe animals were treated with 17β-estradiol (200 µg/kg; E2), red and black maca (1.5 g/kg) for 28 days and exposed at high altitude or sea level.

resultOur findings showed that red and black maca extracts significantly (

conclusionAqueous extract of

Indexed as

hormone replacement therapyhypoxiaLepidium meyeniiovariectomyoxidative stress

Identifiers

PMID33488288
PMCPMC7812464
OpenAlexW3106124438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.