ArticleReproductive medicine and biology2021
Male advantage observed for in vitro fertilization mouse embryos exhibiting early cleavage.
Article in Reproductive medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Oviductal extracellular vesicles miRNA cargo varies in response to embryos and their quality.BMC genomics · 2024Article
- Article
- LPS Administration during Fertilization Affects Epigenetic Inheritance during Embryonic Development.Animals : an open access journal from MDPI · 2023Article
- Morphology-based selection from available euploid blastocysts induces male-skewed sex proportion in the offspring.Journal of assisted reproduction and genetics · 2021Article
- Male advantage observed for in vitro fertilization mouse embryos exhibiting early cleavage.Reproductive medicine and biology · 2021Article
- Glucose-Induced Developmental Dynamics: Understanding Male Prevalence in Early Mouse Embryo Stages.Reproductive medicine and biologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMouse embryos forming blastocoele early vs those forming late are predominantly male. We examined whether the male advantage could be recognized at an earlier stage of development.
methodsThe IVF embryos were classified into early, intermediate, and late development groups based on the time of the third cleavage, and the
resultsApproximately 90% of the early-developing embryos that exhibited third cleavage as early as 47 hours after insemination were male when analyzed using PCR at the blastocyst stage. PCR analysis showed that 61% of the intermediate-developing embryos (third cleavage occurring 48-50 hours after insemination) and 45% of late-developing embryos (third cleavage occurring at 51 hours or later postinsemination) were male. After embryo transfer, the early-developing embryos produced 80% males, while intermediate- and late-developing embryos produced 56% and 45% males, respectively.
conclusionsMale embryos tend to develop faster than female embryos during early stage of preimplantation in mice.
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Registered trials
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