Evidence map›Paper›PMID 33488265›Full record

ArticleTurkish journal of chemistry2020

Fabrication and characterization of boric acid-crosslinked ethyl cellulose and polyvinyl alcohol films as potential drug release systems for topical drug delivery.

Nasrin Aliasgharlou, Farzin Asghari Sana, Saba Khoshbakht, Pezhman Zolfaghari, Hamed Charkhian

Abstract read
In one paragraph

Article in Turkish journal of chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nasrin AliasgharlouDepartment of Chemistry, Faculty of Science, Urmia University, Urmia Iran.ORCID https://orcid.org/0000-0002-2937-8563
Farzin Asghari SanaDepartment of Nanotechnology & Nanomedicine, Hacettepe University, Ankara Turkey.ORCID https://orcid.org/0000-0002-6602-0448
Saba KhoshbakhtDepartment of Pharmaceutics, School of Pharmacy, Urmia University of Medical Science, Urmia Iran.ORCID https://orcid.org/0000-0002-0866-865X
Pezhman ZolfaghariDepartment of Chemical Engineering, Faculty of Chemical and Petroleum Engineering, University of Tabriz, Tabriz Iran.ORCID https://orcid.org/0000-0002-3199-6782
Hamed CharkhianYoung Researchers Club, Urmia Branch, Islamic Azad University, Urmia Iran.ORCID https://orcid.org/0000-0002-7035-3704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, boric acid (BA) is employed as a crosslinking agent to improve the characteristics of two commonly used polymeric films, ethyl cellulose (EC) and polyvinyl alcohol (PVA), for topical drug delivery applications. The developed films are characterized by FTIR spectroscopy and SEM analysis. The results show that the surfaces of the prepared films are even and transparent, except for the BA-modified EC sample. The initial cumulative release for erythromycin (EM) is found to be 0.30 and 0.36 mg/mL for EC and PVA films, which drops to 0.25 and 0.20 mg/mL after BA crosslinking, respectively, after 1 h at 25 °C. Further, the developed formulations are stable for 75 days. Also, the antibacterial activity of the developed formulations is investigated against

Indexed as

boric acidDrug delivery systemerythromycinethyl cellulosepolymeric filmpolyvinyl alcohol

Identifiers

PMID33488265
PMCPMC7763109

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.