Evidence map›Paper›PMID 33488113›Full record

ArticlePharmacogenomics and personalized medicine2021

Genetic Interaction of

Zhaoshi Zheng, Yayun Yan, Qi Guo, Libo Wang, Xuemei Han, Songyan Liu

Open access · goldAbstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. The regulatory function of lncRNA and constructed network in epilepsy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhaoshi ZhengNo. 1 Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130031, People's Republic of China.
Yayun YanNo. 1 Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130031, People's Republic of China.
Qi GuoNo. 1 Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130031, People's Republic of China.
Libo WangNo. 1 Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130031, People's Republic of China.
Xuemei HanNo. 1 Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130031, People's Republic of China.ORCID 0000-0002-5067-2804
Songyan LiuNo. 1 Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130031, People's Republic of China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLong non-coding RNA H19 was highly expressed in the latent period of epilepsy, contributing to apoptosis of hippocampal neurons by targeting let-7b. Transforming growth factor beta receptor 1 ( PATIENTS AND

methodsThe present study consisted of 302 patients with epilepsy and 612 age- and gender-matched controls. The polymorphisms were analyzed using a TaqMan allelic genotyping assay.

resultsThe

conclusionThe current study provides evidence of the rs6478974 TT genotype decreasing the susceptibility to epilepsy by reducing the levels of

Indexed as

genetic susceptibilitylong non-coding RNA H19quantitative PCRtransforming growth factor beta receptor 1

Identifiers

PMID33488113
PMCPMC7814234
OpenAlexW3119951406

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.