Evidence map›Paper›PMID 33487997›Full record

ArticleVeterinary world2020

Post-calving umbilical cord tissue offcut: A potential source for the isolation of bovine mesenchymal stem cells.

Parishma Debbarma, Tanmay Mondal, Camelia Manna, Kuldeep Kumar, Joydip Mukherjee, Bikash Chandra Das, Sadhan Bag, Kinsuk Das

Open access · goldAbstract read
In one paragraph

Article in Veterinary world, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. An Update on Applications of Cattle Mesenchymal Stromal Cells.Animals : an open access journal from MDPI · 2022
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Parishma DebbarmaDepartment of Veterinary Physiology, West Bengal University of Animal and Fishery Sciences, Kolkata, West Bengal, India.
Tanmay MondalDivision of Physiology and Climatology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India.
Camelia MannaDepartment of Veterinary Physiology, West Bengal University of Animal and Fishery Sciences, Kolkata, West Bengal, India.
Kuldeep KumarDivision of Physiology and Climatology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India.
Joydip MukherjeeDepartment of Veterinary Physiology, West Bengal University of Animal and Fishery Sciences, Kolkata, West Bengal, India.
Bikash Chandra DasEastern Regional Station, ICAR-Indian Veterinary Research Institute, Kolkata, West Bengal, India.
Sadhan BagDivision of Physiology and Climatology, ICAR-Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India.
Kinsuk DasDepartment of Veterinary Physiology, West Bengal University of Animal and Fishery Sciences, Kolkata, West Bengal, India.
Indian Veterinary Research Institute · INWest Bengal University of Animal and Fishery Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimVeterinary health care is an emergent area in animal sciences and innovative therapeutic approaches happen to be imperative in the present days. In view of the importance of cattle health and production, it is necessary to take up contemporary approach of stem cell therapy in this sector also. This study aimed to standardize an explant culture method of bovine umbilical tissue offcut to isolate mesenchymal stem cells (MSCs) because considerable efforts are required for ensuring easy accessibility and availability of MSCs in bulk quantity, as well as in establishing and characterizing the cell lines. MATERIALS AND

methodsThe umbilical cord (UC) tissue matrix offcut was collected after calving. A simplified

resultsA considerable exponential growth rate of the UC-derived cells was noticed. In addition to their confirmation as MSCs, the cells also exhibited plastic adherent property and maintained the spindle-shaped morphology throughout the

conclusionThis simplified method of isolation and culture of bovine multipotent MSCs from the UC offcut collected after calving could be extrapolated for the greater availability of the cells for prospective therapeutic applications.

Indexed as

cattleisolationmesenchymal stem cellsumbilical cord tissue

Identifiers

PMID33487997
PMCPMC7811551
OpenAlexW3113660857

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.