Evidence map›Paper›PMID 33487991›Full record

ArticleVeterinary world2020

A novel

Domenico Ventrella, Roberta Salaroli, Alberto Elmi, Giacomo Carnevali, Monica Forni, Fabio Baldi, Maria Laura Bacci

Abstract read
In one paragraph

Article in Veterinary world, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Domenico VentrellaDepartment of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO), Italy.
Roberta SalaroliDepartment of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO), Italy.
Alberto ElmiDepartment of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO), Italy.
Giacomo CarnevaliDepartment of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO), Italy.
Monica ForniDepartment of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO), Italy.
Fabio BaldiCenter for the Study of Diseases of the Esophagus, University of Bologna, Bologna, Italy.
Maria Laura BacciDepartment of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia (BO), Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of the study was to set up a porcine MATERIALS AND

methodsThirteen esophagi, collected at a slaughterhouse, were ablated of their sphincters, pinned upright on a support, and placed in a thermostatic hood at 37°C with two infusion tubes and an MII-pH probe inserted in the top end. Three esophagi (histology controls) were only left in the hood for 3.5 h before sampling, while the remaining organs underwent the experimental protocol including saline infusion and recovery recording, and acid solution infusion and recovery recording.

resultsMII-pH analysis highlighted a significantly stronger decrease during acid infusion when compared to saline, but a better post-infusion recovery for saline solution. At the end of the protocol, MII was still statistically lower than baseline. The acid-damaged esophagi significantly absorbed more EB dye, and histology revealed strong mucosal exfoliation.

conclusionThe proposed model of esophageal acid damage seems to be repeatable, reliable, and achievable using organs collected at the slaughterhouse. MII recording proved to have good sensitivity in detecting mucosal alterations also in

Indexed as

esophagus ex vivo modelEvans blue permeability assaygastroesophageal reflux diseasemultichannel intraluminal impedancepig

Identifiers

PMID33487991
PMCPMC7811544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.