Evidence map›Paper›PMID 33487926›Full record

ArticleJournal of medical physics

Dose Calculation Comparisons between Three Modern Treatment Planning Systems.

Courtney Bosse, Ganesh Narayanasamy, Daniel Saenz, Pamela Myers, Neil Kirby, Karl Rasmussen, Panayiotis Mavroidis, Niko Papanikolaou, Sotirios Stathakis

Open access · diamondAbstract read
In one paragraph

Article in Journal of medical physics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  7. MR-guided stereotactic radiation therapy for head and neck cancers.Clinical and translational radiation oncology · 2024
    Article
  8. Are offline ART decisions for NSCLC impacted by the type of dose calculation algorithm?Technical innovations & patient support in radiation oncology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Dosimetric accuracy of three dose calculation algorithms for radiation therapy of in situ non-small cell lung carcinoma.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022
    Article
  13. Article
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  17. Article
  18. Impact of Minimum Segment Width on VMAT Plan Quality for Nasopharyngeal Carcinoma.Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Courtney BosseRadiation Oncology, Colorado Associates in Medical Physics, Colorado Springs, CO 80907, USA.
Ganesh NarayanasamyDepartment of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Daniel SaenzMays Cancer Center, MD Anderson Cancer Center, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Pamela MyersMays Cancer Center, MD Anderson Cancer Center, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Neil KirbyMays Cancer Center, MD Anderson Cancer Center, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Karl RasmussenMays Cancer Center, MD Anderson Cancer Center, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Panayiotis MavroidisDepartment of Radiation Oncology, University of North Carolina, Chapel Hill, NC, USA.
Niko PapanikolaouMays Cancer Center, MD Anderson Cancer Center, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
Sotirios StathakisMays Cancer Center, MD Anderson Cancer Center, University of Texas Health Science Center San Antonio, San Antonio, TX, USA.
The University of Texas Health Science Center at San Antonio · USMays Cancer Center at UT Health San AntonioThe University of Texas MD Anderson Cancer Center · USUniversity of Arkansas for Medical Sciences · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMonaco treatment planning system (TPS) version 5.1 uses a Monte-Carlo (MC)-based dose calculation engine. The aim of this study is to verify and compare the Monaco-based dose calculations with both Pinnacle MATERIALS AND

methodsFor this study, 18 previously treated lung and head-and-neck (HN) cancer patients were chosen to compare the dose calculations between Pinnacle, Monaco, and Eclipse. Plans were chosen from those that had been treated using the Elekta VersaHD or a Novalis Tx linac. All of the treated volumetric-modulated arc therapy plans used 6 MV or 10 MV photon beams. The original plans calculated with CCCS or AAA along with the recalculated ones using MC from the three TPS were exported into Velocity software for intercomparison.

resultsTo compare the dose calculations, Planning target volume (PTV) heterogeneity indexes and conformity indexes were calculated from the dose volume histograms (DVH) of all plans. While mean lung dose (MLD), lung V5 and V20 values were recorded for lung plans, the computed dose to parotids, brainstem, and mandible were documented for HN plans. In plan evaluation, percent differences of the above dosimetric values in Monaco computation were compared against each of the other TPS computations.

conclusionIt could be concluded through this research that there can be differences in the calculation of dose across different TPSs. Although relatively small, these differences could become apparent when compared using DVH. These differences most likely arise from the different dose calculation algorithms used in each TPS. Monaco employs the MC allowing it to have much more detailed calculations that result in it being seen as the most accurate and the gold standard.

Indexed as

Radiation dose comparisonradiotherapy plan similaritytreatment planning system comparison

Identifiers

PMID33487926
PMCPMC7810148
OpenAlexW3093048654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.