Evidence map›Paper›PMID 33487654›Full record

ArticleThe Canadian journal of hospital pharmacy2021

Identification of Staphylococci by Polymerase Chain Reaction Directly from a Positive Blood Culture and Effect on Patient Care.

Molly Wade-Cummings, Jonathan F Mailman, Michelle L Degelman, Casey Phillips, Jason R Vanstone

Open access · bronzeAbstract read
PubMed Full text at PMC
In one paragraph

Article in The Canadian journal of hospital pharmacy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Molly Wade-Cummings, BSc, is with the College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan.
Jonathan F Mailman, BSc(Pharm), ACPR, PharmD, CD, is with the Department of Pharmacy Services, Saskatchewan Health Authority, Regina, Saskatchewan, and the College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan.
Michelle L Degelman, MSc, is with Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, Regina, Saskatchewan.
Casey Phillips, BSP, PharmD, is with the Antimicrobial Stewardship Program, Saskatchewan Health Authority, Regina, Saskatchewan.
Jason R Vanstone, PhD, is with Stewardship and Clinical Appropriateness, Saskatchewan Health Authority, Regina, Saskatchewan.
Saskatchewan Health Authority · CAUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs one of the most common bloodstream infections worldwide,

objectivesThe primary objective was to assess concordance between testing based on polymerase chain reaction (PCR) and the current gold standard, culture and sensitivity testing; the secondary objective was to assess the impact of this technology on patient care.

methodsA pre-post intervention retrospective chart review was used to document the hospital course of patients with a diagnosis of

resultsIn total, 98 and 99 patients met the inclusion criteria before and after implementation of the PCR-based diagnostic system, respectively. PCR-based results displayed 99.8% concordance (440/441 total samples) with results from culture and sensitivity testing. The time to optimal therapy was significantly shorter after implementation, by a mean of 22.8 h (

conclusionsThe study findings support the utility of using a direct-from-positive-blood-culture PCR-based diagnostic tool as the primary method of identifying

Indexed as

antimicrobial stewardshipbacteremiabactériémiediagnostic testingGeneXpertgestion de l’utilisation des antimicrobienspolymerase chain reactionréaction en chaîne par polymérasetest de diagnostic

Identifiers

PMID33487654
PMCPMC7801333
OpenAlexW3120312208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.