Evidence map›Paper›PMID 33487528›Full record

Trial reportThe International journal on drug policy2021

Brief interventions to prevent excessive alcohol use in adolescents at low-risk presenting to Emergency Departments: Three-arm, randomised trial of effectiveness and cost-effectiveness.

Paolo Deluca, Simon Coulton, Mohammed Fasihul Alam, Sadie Boniface, David Cohen, Kim Donoghue, Eilish Gilvarry, Eileen Kaner, Ian Maconochie, Paul McArdle and 10 more

Open access · hybridAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in The International journal on drug policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 11 institutions in 2 countries.

Paolo DelucaInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London UK. Electronic address: paolo.deluca@kcl.ac.uk.
Simon CoultonCentre for Health Services Studies, University of Kent, Canterbury, UK.
Mohammed Fasihul AlamCollege of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Sadie BonifaceInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London UK.
David CohenHealth Economics and Policy Research Unit, University of South Wales, Pontypridd, UK.
Kim DonoghueInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London UK.
Eilish GilvarryNorthumberland Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.
Eileen KanerPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Ian MaconochiePaediatric Emergency Medicine, Imperial College, London, UK.
Paul McArdleNorthumberland Tyne and Wear NHS Foundation Trust, Newcastle upon Tyne, UK.
Ruth McGovernPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Dorothy Newbury-BirchSchool of Social Sciences, Humanities and Law, Teesside University, Middlesbrough, UK.
Robert PattonSchool of Psychology, University of Surrey, Guildford, UK.
Tracy Pellatt-HigginsCentre for Health Services Studies, University of Kent, Canterbury, UK.
Ceri PhillipsSwansea Centre for Health Economics, College of Human and Health Sciences, Swansea University, Swansea, Wales, UK.
Thomas PhillipsInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London UK; Institute for Clinical and Applied Health Research, University of Hull, Hull, UK.
Rhys D PockettSwansea Centre for Health Economics, College of Human and Health Sciences, Swansea University, Swansea, Wales, UK.
Ian RussellMedical School, Swansea University, Swansea, Wales, UK.
John StrangInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London UK.
Colin DrummondInstitute of Psychiatry, Psychology & Neuroscience, King's College London, London UK.
King's College London · GBSwansea University · GBCumbria Northumberland Tyne and Wear NHS Foundation Trust · GBNewcastle University · GBUniversity of Kent · GBImperial College London · GBQatar University · QATeesside University · GBUniversity of Hull · GBUniversity of South Wales · GBUniversity of Surrey · GB

Funding

Department of Health RP-PG-0609-10162Medical Research Council G0701681Medical Research Council G0701818Medical Research Council MR/K02325X/1Medical Research Council MR/N00616X/1
6 · The paper itself

Abstract

backgroundAlcohol consumption and related harm increase rapidly from the age of 12 years. We evaluated whether alcohol screening and brief intervention is effective and cost-effective in delaying hazardous or harmful drinking amongst low-risk or abstaining adolescents attending Emergency Departments (EDs).

methodsThis ten-centre, three-arm, parallel-group, single-blind, pragmatic, individually randomised trial screened ED attenders aged between 14 and 17 years for alcohol consumption. We sampled at random one third of those scoring at most 2 on AUDIT-C who had access to the internet and, if aged under 16, were Gillick competent or had informed consent from parent or guardian. We randomised them between: screening only (control intervention); one session of face-to-face Personalised Feedback and Brief Advice (PFBA); and PFBA plus an electronic brief intervention (eBI) on smartphone or web. We conducted follow-up after six and 12 months. The principal outcomes were alcohol consumed over the 3 months before 12-month follow up, measured by AUDIT-C; and quality-adjusted life-years.

findingsBetween October 2014 and May 2015, we approached 5,016 eligible patients of whom 3,326 consented to be screened and participate in the trial; 2,571 of these were low-risk drinkers or abstainers, consuming an average 0.14 units per week. We randomised: 304 to screening only; 285 to PFBA; and 294 to PFBA and eBI. We found no significant difference between groups, notably in weekly alcohol consumption: those receiving screening only drank 0.10 units (95% confidence interval 0.05 to 0.18); PFBA 0.12 (0.06 to 0.21); PFBA and eBI 0.10 (0.05 to 0.19).

interpretationWhile drinking levels remained low in this population, this trial found no evidence that PFBA with or without eBI was more effective than screening alone in reducing or delaying alcohol consumption.

Indexed as

AlcoholismCrisis InterventionAdolescentAlcohol DrinkingCost-Benefit AnalysisEmergency Service, HospitalHumansSingle-Blind MethodAdolescentAlcoholAlcohol screeningBrief interventionCost-effectivenessEffectivenessElectronic brief interventionEmergency departmentLow riskRandomised controlled trial

Identifiers

PMID33487528
PMCPMC8261826
OpenAlexW3122057723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.