Evidence map›Paper›PMID 33487466›Full record

ArticleVaccine2021

Advancing innovation for vaccine manufacturers from developing countries: Prioritization, barriers, opportunities.

Benoit Hayman, Alex Bowles, Beth Evans, Elizabeth Eyermann, Lyudmila Nepomnyashchiy, Sonia Pagliusi

Open access · hybridAbstract read
In one paragraph

Article in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Bioengineering (Basel, Switzerland) · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Benoit HaymanDCVMN International, Route de Crassier 7, 1262 Nyon, Switzerland. Electronic address: b.hayman@dcvmn.net.
Alex BowlesClinton Health Access Initiative, 383 Dorchester Ave, Suite 400, Boston, MA 02127, USA. Electronic address: abowles@clintonhealthaccess.org.
Beth EvansClinton Health Access Initiative, 383 Dorchester Ave, Suite 400, Boston, MA 02127, USA. Electronic address: bevans@clintonhealthaccess.org.
Elizabeth EyermannClinton Health Access Initiative, 383 Dorchester Ave, Suite 400, Boston, MA 02127, USA. Electronic address: eeyermann@clintonhealthaccess.org.
Lyudmila NepomnyashchiyClinton Health Access Initiative, 383 Dorchester Ave, Suite 400, Boston, MA 02127, USA. Electronic address: mila.nepomnyashchiy@gmail.com.
Sonia PagliusiDCVMN International, Route de Crassier 7, 1262 Nyon, Switzerland. Electronic address: s.pagliusi@dcvmn.net.
Clinton Health Access Initiative · USDeveloping Countries Vaccine Manufactures Network · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of novel vaccines and improving existing vaccines is critical to addressing areas of unmet or under-addressed health needs globally and to improving existing vaccination coverage and equity. However, vaccine innovation is costly and highly complex. To understand how vaccine manufacturers from developing countries approach innovation, a survey was conducted among company members of the Developing Countries Vaccine Manufacturers Network, in collaboration with the Clinton Health Access Initiative. The survey confirmed that vaccine manufacturers from developing countries are committed to vaccine innovation: 95% of respondents have interest in pursuing vaccine innovation, with strategies targeted towards supplying to low- and middle-income countries. Key barriers to innovation were also surveyed, with respondents highlighting challenges regarding access to in-licensing or joint venture partnerships, financing, and regulatory barriers. Opportunities for innovation are also discussed.

Indexed as

Developing CountriesVaccinesGlobal HealthVaccination CoverageVaccinesDeveloping countriesInnovation financingPartnershipsRegulatory barriersVaccine development

Identifiers

PMID33487466
PMCPMC7909323
OpenAlexW3123403395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.