Evidence map›Paper›PMID 33487070›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Correspondence between patterns of cerebral blood flow and structure in adolescents with and without bipolar disorder.

Nicholas J Luciw, Simina Toma, Benjamin I Goldstein, Bradley J MacIntosh

Open access · hybridAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Changes in the structural brain connectome over the course of a nonrandomized clinical trial for acute mania.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicholas J LuciwDepartment of Medical Biophysics, University of Toronto, Toronto, Canada.ORCID 0000-0003-4043-990X
Simina TomaDepartment of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Canada.
Benjamin I GoldsteinHurvitz Brain Sciences, Sunnybrook Research Institute, University of Toronto, Toronto, Canada.
Bradley J MacIntoshDepartment of Medical Biophysics, University of Toronto, Toronto, Canada.ORCID 0000-0001-7300-2355
Sunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adolescence is a period of rapid development of the brain's inherent functional and structural networks; however, little is known about the region-to-region organization of adolescent cerebral blood flow (CBF) or its relationship to neuroanatomy. Here, we investigate both the regional covariation of CBF MRI and the covariation of structural MRI, in adolescents with and without bipolar disorder. Bipolar disorder is a disease with increased onset during adolescence, putative vascular underpinnings, and evidence of anomalous CBF and brain structure. In both groups, through hierarchical clustering, we found CBF covariance was principally described by clusters of regions circumscribed to the left hemisphere, right hemisphere, and the inferior brain; these clusters were spatially reminiscent of cerebral vascular territories. CBF covariance was associated with structural covariance in both the healthy group (n = 56;

Indexed as

AdolescentBipolar DisorderBrainCase-Control StudiesCerebrovascular CirculationFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleSpin LabelsYoung AdultSpin LabelsAdolescencebipolar disordercerebral blood flowMRIstructural covariance

Identifiers

PMID33487070
PMCPMC8323335
OpenAlexW3121733654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.