Trial reportHypertension (Dallas, Tex. : 1979)2021
Effect of Reducing Ambient Traffic-Related Air Pollution on Blood Pressure: A Randomized Crossover Trial.
Trial report in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of PM2.5 Reduction Interventions on Cardiovascular Indicators: A Meta-analysis.Cardiovascular toxicology · 2025Pooled it
- Effect of HEPA Filtration Air Purifiers on Blood Pressure: A Pragmatic Randomized Crossover Trial.Journal of the American College of Cardiology · 2025Trial
- Reaction to at-home air purifiers installed to reduce traffic-related air pollution in near-highway residences.Trials · 2024Trial
- Blood Pressure Effect of Traffic-Related Air Pollution : A Crossover Trial of In-Vehicle Filtration.Annals of internal medicine · 2023Trial
- Health Benefits of Air Purification: A Systematic Review.Environment & health (Washington, D.C.) · 2026Review
- Article
- Effects of Air Pollution on Dialysis and Kidney Transplantation: Clinical and Public Health Action.Journal of clinical medicine · 2025Review
- Outdoor temperature as a confounder of blood pressure in randomized trials.The Science of the total environment · 2025Article
- Exposure to Air Pollution and Changes in Resting Blood Pressure from Morning to Evening: The MobiliSense Study.International journal of environmental research and public health · 2025Article
- Effects of physical exercise on cardio-respiratory health of young adults during short-term exposure to varying air pollution levels.BMC public health · 2024Article
- Concentration-Response Functions Relating Concentration and Duration of Ambient Traffic-Related Air Pollution Exposure to Systolic Blood Pressure.Environmental health perspectives · 2024Article
- The Environment and the Heart.Arquivos brasileiros de cardiologia · 2023Article
- Ambient Air Pollution and Stroke: An Updated Review.Stroke · 2023Review
- Adapting an In-Home Randomized Intervention Trial Protocol for COVID-19 Precautions.International journal of environmental research and public health · 2023Article
- Acute exposure to air pollutants increase the risk of acute glaucoma.BMC public health · 2022Article
- Emerging concepts and opportunities for endocrine disruptor screening of the non-EATS modalities.Environmental research · 2022Article
- Short-Term Cumulative Exposure to Ambient Traffic-Related Black Carbon and Blood Pressure: MMDA Traffic Enforcers' Health Study.International journal of environmental research and public health · 2021Article
- A randomized crossover trial of HEPA air filtration to reduce cardiovascular risk for near highway residents: Methods and approach.Contemporary clinical trials · 2021Article
- An Evaluation of an Environmental Health Infographic in Community Settings.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Exposure to traffic-related air pollution (TRAP) may contribute to increased prevalence of hypertension and elevated blood pressure (BP) for residents of near-highway neighborhoods. Relatively few studies have investigated the effects of reducing TRAP exposure on short-term changes in BP. We assessed whether reducing indoor TRAP concentrations by using stand-alone high-efficiency particulate arrestance (HEPA) filters and limiting infiltration through doors and windows effectively prevented acute (ie, over a span of hours) increases in BP. Using a 3-period crossover design, 77 participants were randomized to attend three 2-hour-long exposure sessions separated by 1-week washout periods. Each participant was exposed to high, medium, and low TRAP concentrations in a room near an interstate highway. Particle number concentrations, black carbon concentrations, and temperature were monitored continuously. Systolic BP (SBP), diastolic BP, and heart rate were measured every 10 minutes. Outcomes were analyzed with a linear mixed model. The primary outcome was the change in SBP from 20 minutes from the start of exposure. SBP increased with exposure duration, and the amount of increase was related to the magnitude of exposure. The mean change in SBP was 0.6 mm Hg for low exposure (mean particle number and black carbon concentrations, 2500 particles/cm
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.