Evidence map›Paper›PMID 33486978›Full record

ArticleAIDS care2021

Drug and alcohol use among people living with HIV in care in the United States by geographic region.

Heidi M Crane, Robin M Nance, Bridget M Whitney, Stephanie Ruderman, Judith I Tsui, Geetanjali Chander, Mary E McCaul, Bryan Lau, Kenneth H Mayer, D Scott Batey and 12 more

Abstract read
In one paragraph

Article in AIDS care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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  12. Changes in the Prevalence of Non-AIDS Conditions Among Hospitalized Persons With HIV in the United States and Canada, 2008-2018.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Heidi M CraneDepartment of Medicine, University of Washington, Seattle, WA, USA.
Robin M NanceDepartment of Medicine, University of Washington, Seattle, WA, USA.
Bridget M WhitneyDepartment of Medicine, University of Washington, Seattle, WA, USA.
Stephanie RudermanDepartment of Epidemiology, University of Washington, Seattle, WA, USA.
Judith I TsuiDepartment of Medicine, University of Washington, Seattle, WA, USA.
Geetanjali ChanderDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-2216-6330
Mary E McCaulDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.
Bryan LauDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, USA.
Kenneth H MayerFenway Institute and Department of Medicine, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-7460-733X
D Scott BateyDepartment of Social Work, University of Alabama at Birmingham, Birmingham, AL, USA.
Steven A SafrenDepartment of Psychology, University of Miami, Miami FL, USA.ORCID 0000-0002-0121-0806
Richard D MooreDepartment of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Joseph J EronDepartment of Medicine, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0002-4938-0644
Sonia NapravnikDepartment of Medicine, University of North Carolina, Chapel Hill, NC, USA.
W Chris MathewsDepartment of Medicine, University of California at San Diego, San Diego, CA, USA.
Rob J FredericksenDepartment of Medicine, University of Washington, Seattle, WA, USA.
Andrew W HahnDepartment of Medicine, University of Washington, Seattle, WA, USA.
Michael J MugaveroDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
William B LoberDepartment of Medicine, University of Washington, Seattle, WA, USA.
Michael S SaagDepartment of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Mari M KitahataDepartment of Medicine, University of Washington, Seattle, WA, USA.
Joseph A C DelaneyDepartment of Epidemiology, University of Washington, Seattle, WA, USA.

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Alcohol Research Consortium in HIV: Relapse Prevention ArmP01AA029544 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI HUTTON, HEIDI · 2021 to 2025
$7.1M
3/4 Alcohol Research Consortium in HIV - Epidemiological Research Arm (ARCH-ERA)U01AA020793 · NIAAA · UNIVERSITY OF WASHINGTON · PI CRANE, HEIDI M., LAU, BRYAN · 2011 to 2020
$5.8M
Substance use patterns and contexts: impact on epigenetic age and prevention strategies in an HIV clinical care cohortR01DA047045 · NIDA · UNIVERSITY OF WASHINGTON · PI Heidi M. Crane, Joseph Austin Delaney · 2018 to 2026
$5.1M
Integration of Evidence-based Alcohol Interventions into HIV CareU01AA020802 · NIAAA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CROPSEY, KAREN L, MUGAVERO, MICHAEL J · 2011 to 2020
$4.2M
1/4 Alcohol Research Consortium in HIV-Administrative Core (ARCH-AC)U24AA020801 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI, MCCAUL, MARY E · 2011 to 2021
$3.5M
Mentoring and Patient Oriented Research at the Nexus of Unhealthy Alcohol Use and HIVK24AA027483 · NIAAA · UNIVERSITY OF WASHINGTON · PI GEETANJALI CHANDER · 2019 to 2026
$1.3M
NIAAA NIH HHS K24 AA027483NIAAA NIH HHS P01 AA029544NIAAA NIH HHS U01 AA020793NIAAA NIH HHS U01 AA020802NIAAA NIH HHS U24 AA020801NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI060354NIAID NIH HHS P30 AI094189NIAID NIH HHS R24 AI067039NIDA NIH HHS R01 DA047045
6 · The paper itself

Abstract

Substance use in the U.S. varies by geographic region. Opioid prescribing practices and marijuana, heroin, and methamphetamine availability are evolving differently across regions. We examined self-reported substance use among people living with HIV (PLWH) in care at seven sites from 2017-2019 to understand current regional substance use patterns. We calculated the percentage and standardized percentage of PLWH reporting current drug use and at-risk and binge alcohol use by U.S. Census Bureau geographic region and examined associations in adjusted logistic regression analyses. Among 7,686 PLWH, marijuana use was the most prevalent drug (30%), followed by methamphetamine/crystal (8%), cocaine/crack (7%), and illicit opioids (3%). One-third reported binge alcohol use (32%). Differences in percent of current use by region were seen for marijuana (24-41%) and methamphetamine/crystal (2-15%), with more use in the West and Northeast, and binge alcohol use (26-40%). In adjusted analyses, PLWH in the Midwest were significantly less likely to use methamphetamine/crystal (aOR: 0.13;0.06-0.25) or illicit opioids (aOR:0.16;0.05-0.53), and PLWH in the Northeast were more likely to use cocaine/crack (aOR:1.59;1.16-2.17), compared to PLWH in the West. Understanding differences in substance use patterns in the current era, as policies continue to evolve, will enable more targeted interventions in clinical settings among PLWH.

Indexed as

Crack CocaineHIV InfectionsAlcohol DrinkingAnalgesics, OpioidHumansPractice Patterns, Physicians'United StatesAnalgesics, OpioidCrack Cocainealcohol useDrug useHIVmarijuanamethamphetamine

Identifiers

PMID33486978
PMCPMC9104760

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.