Evidence map›Paper›PMID 33486968›Full record

ArticleCirculation research2021

Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes.

Jonas Peper, Daniel Kownatzki-Danger, Gunnar Weninger, Fitzwilliam Seibertz, Julius Ryan D Pronto, Henry Sutanto, David Pacheu-Grau, Robin Hindmarsh, Sören Brandenburg, Tobias Kohl and 12 more

Open access · bronzeAbstract read
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In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Lactylation in cardiac repair: Nexus and therapeutic opportunity.Journal of molecular and cellular cardiology plus · 2026
    Review
  3. Article
  4. Journal of the American Heart Association · 2026
    Article
  5. Article
  6. Proteomics of the heart.Physiological reviews · 2024
    Review
  7. High-throughput methods for cardiac cellular electrophysiology studies: the road to personalized medicine.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Caveolin-3 and Caveolae regulate ventricular repolarization.Journal of molecular and cellular cardiology · 2023
    Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 10 institutions in 6 countries.

Jonas PeperCellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen (J.P., D.K.-D., G.W., S.B., T.K., G.H., J.W., S.E.L.), University Medical Center Göttingen.
Daniel Kownatzki-DangerCellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen (J.P., D.K.-D., G.W., S.B., T.K., G.H., J.W., S.E.L.), University Medical Center Göttingen.
Gunnar WeningerCellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen (J.P., D.K.-D., G.W., S.B., T.K., G.H., J.W., S.E.L.), University Medical Center Göttingen.
Fitzwilliam SeibertzInstitute of Pharmacology and Toxicology (F.S., J.R.D.P., N.V.), University Medical Center Göttingen.
Julius Ryan D ProntoInstitute of Pharmacology and Toxicology (F.S., J.R.D.P., N.V.), University Medical Center Göttingen.
Henry SutantoCardiology, Cardiovascular Research Institute Maastricht, Maastricht University (H.S., J.H.).
David Pacheu-GrauCellular Biochemistry, University Medical Center, Georg-August-University (D.P.G., P.R.).
Robin HindmarshCardiology & Pneumology (J.P., D.K.-D., G.W., R.H., S.B., T.K., G.H., J.W., L.C., S.E.L.), University Medical Center Göttingen.
Sören BrandenburgCellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen (J.P., D.K.-D., G.W., S.B., T.K., G.H., J.W., S.E.L.), University Medical Center Göttingen.
Tobias KohlCellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen (J.P., D.K.-D., G.W., S.B., T.K., G.H., J.W., S.E.L.), University Medical Center Göttingen.
Gerd HasenfussCellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen (J.P., D.K.-D., G.W., S.B., T.K., G.H., J.W., S.E.L.), University Medical Center Göttingen.
Michael GotthardtNeuromuscular and Cardiovascular Cell Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin (M.G.).
Eva A Rog-ZielinskaUniversity Heart Center, Faculty of Medicine, University of Freiburg (E.A.R.-Z.).
Bernd WollnikInstitute of Human Genetics (B.W.), University Medical Center Göttingen.
Peter RehlingCellular Biochemistry, University Medical Center, Georg-August-University (D.P.G., P.R.).
Henning UrlaubBioanalytics, Institute of Clinical Chemistry (H.U., C.L.), University Medical Center Göttingen.
Jörg WegenerCellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen (J.P., D.K.-D., G.W., S.B., T.K., G.H., J.W., S.E.L.), University Medical Center Göttingen.
Jordi HeijmanCardiology, Cardiovascular Research Institute Maastricht, Maastricht University (H.S., J.H.).
Niels VoigtInstitute of Pharmacology and Toxicology (F.S., J.R.D.P., N.V.), University Medical Center Göttingen.
Lukas CyganekDZHK (German Centre for Cardiovascular Research), partner site Göttingen (F.S., S.B., T.K., G.H., J.W., N.V., L.C., S.E.L.).
Christof LenzBioanalytics, Institute of Clinical Chemistry (H.U., C.L.), University Medical Center Göttingen.
Stephan E LehnartCellular Biophysics and Translational Cardiology Section, Heart Research Center Göttingen (J.P., D.K.-D., G.W., S.B., T.K., G.H., J.W., S.E.L.), University Medical Center Göttingen.
German Centre for Cardiovascular Research · DEKPJ Ampang Puteri Specialist Hospital · MYBioanalytica (Switzerland) · CHMaastricht University · NLUniversity of Göttingen · DEInstitute of Human Genetics · PLMax Delbrück Center · DENanoscale Microscopy and Molecular Physiology of the Brain Cluster of Excellence 171 — DFG Research Center 103 · DEUniversity of Freiburg · DEUniversity of Maryland, Baltimore · US

Funding

British Heart Foundation FS/15/3/31047
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

Action PotentialsCaveolin 3Cells, CulturedHumansLactic AcidLoss of Function MutationMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersMyocytes, CardiacProtein BindingSodiumSodium-Potassium-Exchanging ATPaseSymportersCAV3 protein, humanCaveolin 3Lactic AcidMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersSodiumSodium-Potassium-Exchanging ATPaseSymportersmass spectrometrymitochondriamuscular dystrophiesproteomicssarcolemma

Identifiers

PMID33486968
OpenAlexW3125999553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.