Evidence map›Paper›PMID 33486673›Full record

ArticleJournal of thrombosis and thrombolysis2021

Assessment of provider practices regarding venous thromboembolism management and prevention in pediatric acute leukemia patients.

Melanie Degliuomini, Victoria Cooley, Elizabeth Mauer, Linda M Gerber, Suchitra Acharya, Nicole Kucine

Abstract read
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In one paragraph

Article in Journal of thrombosis and thrombolysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pulmonary Embolism Secondary to Intravenous Immunoglobulin in a Child with LeukemiaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Melanie DegliuominiDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA. degliuom@mskcc.org.ORCID http://orcid.org/0000-0003-2078-4706
Victoria CooleyDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Elizabeth MauerDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Linda M GerberDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Suchitra AcharyaCohen Children's Medical Center of New York, New Hyde Park, New York, NY, USA.
Nicole KucineDepartment of Pediatrics, Weill Cornell Medicine, New York, NY, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Despite the known occurrence of venous thromboembolism (VTE) in the pediatric oncology population, there are no leukemia-specific VTE treatment guidelines. The primary objective of this study was to assess current practices regarding the management and prevention of VTE in the pediatric acute lymphoblastic leukemia (ALL) population. We performed a cross sectional, anonymous, electronic survey of members of the American Society of Hematology and the pediatric subcommittee of VENUS (VTE Network US of the Hemostasis and Thrombosis Research Society). Survey items included questions on demographics and clinical practice. Of 870 surveys distributed, 154 were submitted, giving a 17.7% response rate. Treatment duration, re-imaging timeline, and class of anticoagulants used were reported for catheter-associated deep vein thrombus, pulmonary embolism, and cerebral venous sinus thrombosis. While there are some common themes regarding VTE management, there is notable variation in the overall practice as well as with the decision to continue anticoagulation in the presence of thrombocytopenia. Given the variation seen, a multi-center, prospective clinical trial is urgently needed for developing consensus guidelines for the management of VTE in children with ALL.

Indexed as

Precursor Cell Lymphoblastic Leukemia-LymphomaThrombosisVenous ThromboembolismAnticoagulantsChildCross-Sectional StudiesHumansProspective StudiesAnticoagulantsAnticoagulationPediatric leukemiaThromboembolismThromboprophylaxis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.