Evidence map›Paper›PMID 33486548›Full record

ArticleJournal of molecular evolution2021

Optimal Evolution of the Standard Genetic Code.

Michael Yarus

Abstract read
In one paragraph

Article in Journal of molecular evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Fitting the standard genetic code into its triplet table.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  5. Article
  6. Evolution of the genetic code.Transcription · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael YarusDepartment of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, CO, 80309-0347, USA. yarus@colorado.edu.ORCID 0000-0003-0295-9795

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Standard Genetic Code (SGC) exists in every known organism on Earth. SGC evolution via early unique codon assignment, then later wobble, yields coding resembling the near-universal code. Below, later wobble is shown to also create an optimal route to accurate codon assignment. Time of optimal codon assignment matches the previously defined mean time for ordered coding, exhibiting ≥ 90% of SGC order. Accurate evolution is also accessible, sufficiently frequent to appear in populations of 10

Indexed as

Genetic CodeMagnoliopsidaEarth, PlanetEvolution, MolecularCodingCodonEvolveTripletWobble

Identifiers

PMID33486548
PMCPMC7884564

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.