ArticleAtherosclerosis2021
Acute ischemic stroke versus transient ischemic attack: Differential plaque morphological features in symptomatic intracranial atherosclerotic lesions.
Article in Atherosclerosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Intracranial atherosclerotic plaque features on vessel wall imaging predict first ever and recurrence of stroke: a meta-analysis.European radiology · 2025Pooled it
- The effects of moderate-dose statin therapy on intracranial plaques with mild to moderate stenosis: a high-resolution MR vessel wall imaging study.European radiology · 2026Article
- Analysis of Risk Factors Related to Carotid Artery in Patients with Acute Ischemic Stroke.Current medical imaging · 2026Article
- High-resolution MRI-based Radiomics and Machine Learning for Identification of Middle Cerebral Artery Vulnerable PlaquesCurrent medical imaging · 2026Article
- Deep learning-based key point detection algorithm assisting vessel centerline extraction.Quantitative imaging in medicine and surgery · 2025Article
- Differences in plaque curvature in middle cerebral artery stenosis between acute stroke and non-acute stroke.Quantitative imaging in medicine and surgery · 2025Article
- A radiomic model based on 7T intracranial vessel wall imaging for identification of culprit middle cerebral artery plaque associated with subcortical infarctions.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Article
- The predictive value of triglyceride-glucose index on early neurological functional improvement in non-diabetic patients with acute ischemic stroke undergoing intravenous thrombolysis.Frontiers in neurology · 2025Article
- Association of plaque characteristics with long-term stroke recurrence in patients with intracranial atherosclerotic disease: a 3D high-resolution MRI-based cohort study.European radiology · 2024Article
- Towards a Systemic Concept of the Brain Ishemia Stroke: Monte Carlo DrivenCNS & neurological disorders drug targets · 2024Article
- The incomplete circle of Willis is associated with vulnerable intracranial plaque features and acute ischemic stroke.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- VWI-APP: Vessel wall imaging-dedicated automated processing pipeline for intracranial atherosclerotic plaque quantification.Medical physics · 2023Article
- Effect of PCSK9 inhibition in combination with statin therapy on intracranial atherosclerotic stenosis: A high-resolution MRI study.Frontiers in aging neuroscience · 2023 · on this mapArticle
- Multimodal MRI study of the relationship between plaque characteristics and hypoperfusion in patients with transient ischemic attack.Frontiers in neurology · 2023Article
- Follow-up assessment of atherosclerotic plaques in acute ischemic stroke patients using high-resolution vessel wall MR imaging.Neuroradiology · 2022Article
- Intracranial vessel wall segmentation with deep learning using a novel tiered loss function incorporating class inclusion.Medical physics · 2022Article
- Temporal changes in plaque characteristics after treatment and their relationship with stroke recurrence: a quantitative study using magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2022Article
- Application and interpretation of vessel wall magnetic resonance imaging for intracranial atherosclerosis: a narrative review.Annals of translational medicine · 2022Review
- Evaluation of intracranial artery stenosis using time-of-flight magnetic resonance angiography: new wine in an old bottle.European radiology · 2022Article
- Predictive power of high-resolution vessel wall magnetic resonance imaging in ischemic stroke.American journal of translational research · 2022Article
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Authors and funding
17 authors at 5 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
aimsIntracranial atherosclerotic disease (ICAD) is a major etiologic cause for acute ischemic stroke (AIS) and transient ischemic attack (TIA). The study was designed to investigate if differential morphological features exist in symptomatic atherosclerotic lesions between AIS and TIA patients.
methodsThe culprit plaques from 45 AIS patients and 42 TIA patients were analyzed for the degree of stenosis, vessel wall irregularity, normalized wall index (NWI), remodeling index, plaque-wall contrast ratio (CR), high signal intensity on T1-weighted images, plaque enhancement ratio and enhancement grade. These plaque features along with clinical characteristics were compared between AIS and TIA groups as well as between their stenosis degree-matched subgroups.
resultsOverall, grade 2 enhancement (OR 3.85, 95%CI 1.42-10.46, p = 0.006) and hyperlipidemia (OR 3.04, 95%CI 1.13-8.22, p = 0.025) were independent indicators for AIS, whereas high NWI (OR 1.47, 95%CI 0.76-2.86, p = 0.004) was associated with TIA. In the comparison between the subgroups with moderate (30%-69%) stenosis, high plaque-wall CR (OR 5.38, 95%CI 1.39-20.75, p = 0.008) was associated with AIS, whereas high NWI (OR 2.50, 95%CI 0.61-10.00, p = 0.006) was associated with TIA.
conclusionsOur study reveals differential morphological features in symptomatic ICAD lesions between AIS and TIA patients. Probing these features with MR vessel wall imaging may provide insights into the prognosis of patients with ICAD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.