ArticleThe journal of allergy and clinical immunology. In practice2021
Trends in US Emergency Department Visits for Anaphylaxis Among Infants and Toddlers: 2006-2015.
Article in The journal of allergy and clinical immunology. In practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Epidemiological shifts and temporal trends in emergency department anaphylaxis management: An 18-year longitudinal study in northern Thailand.The World Allergy Organization journal · 2026Article
- Model-Informed Dose Selection of Intranasal Epinephrine in Young Children.Journal of clinical pharmacology · 2026Article
- Rising trends in infant ER encounters for food-induced allergic reactions in the era of early allergenic food introduction.The journal of allergy and clinical immunology. Global · 2026Article
- A critical case of anaphylaxis triggered by exercise in a pediatric asthma patient.BMC pediatrics · 2025Article
- Protocol design for the ACTIVATE clinical trial: Exposure to vaginal microbiome in cesarean-delivered infants at high risk for allergies.The journal of allergy and clinical immunology. Global · 2025Article
- Incidence and risk factors correlated with otitis media with effusion in pediatric patients with obstructive sleep apnea: a retrospective nationwide inpatient sample database study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Assessing Preparedness and Preventive Measures for Managing Food Allergy and Anaphylaxis in Primary Schools of Rabigh, Saudi Arabia.International journal of environmental research and public health · 2025Article
- Advocating for the vulnerable: addressing anaphylaxis in infancy through awareness, research, and policy.Pediatric research · 2025Article
- Transepidermal water loss increases during murine food anaphylaxis and reflects reaction severity.Frontiers in immunology · 2025Article
- Incidence and trends of anaphylaxis among inpatients from 2003 to 2023 in Wuhan, China: A multicenter retrospective study.The World Allergy Organization journal · 2024Article
- Prediction of pediatric peanut oral food challenge outcomes using machine learning.The journal of allergy and clinical immunology. Global · 2024Article
- Changes in epinephrine dispensings and allergy hospitalisations in Sweden in the years following the removal of autoinjector co-payments.Frontiers in allergy · 2024Article
- Contemporary trends in anaphylaxis burden and healthcare utilisation in Western Australia: A linked data study.The World Allergy Organization journal · 2023Article
- Transepidermal water loss rises before food anaphylaxis and predicts food challenge outcomes.The Journal of clinical investigation · 2023Article
- Pattern of admissions and outcome in the children emergency department of a tertiary health institution in Southwestern Nigeria: A four-year review.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2023Article
- Cow's milk and hen's egg anaphylaxis: A comprehensive data analysis from the European Anaphylaxis Registry.Clinical and translational allergy · 2023Article
- Children at risk of anaphylaxis: A mixed-studies systematic review of parents' experiences and information needs.PEC innovation · 2022Review
- Anaphylaxis in Brazil between 2011 and 2019.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022Article
- Minimizing the "Kitchen Sink" Approach: De-implementation of Unnecessary Care for Patients with Anaphylaxis in a Pediatric Emergency Department.Pediatric quality & safetyArticle
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundAnaphylaxis is a potentially life-threatening allergic reaction. The overall prevalence of anaphylaxis appears to be rising in children, but temporal trends among infants and toddlers are not well studied.
objectiveTo characterize the trends in US emergency department (ED) visits and hospitalizations among infants and toddlers with anaphylaxis from 2006 to 2015.
methodsWe conducted a study of temporal trends in anaphylaxis among children (age <18 years) and, more specifically, infants and toddlers (age <3 years) presenting to the ED between 2006 and 2015 using a large, nationally representative database. For internal consistency, we defined anaphylaxis using International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis codes and excluded visits with International Classification of Diseases, Tenth Revision, Clinical Modification diagnosis codes (late 2015). We calculated trends in the number and proportion of ED visits and hospitalizations and used multivariable logistic regression to identify predictors of hospitalization.
resultsAmong infants and toddlers, the proportion of ED visits for anaphylaxis per year increased from 20 per 100,000 visits to 50 per 100,000 visits (P
conclusionsIn a large, nationally representative US database, from 2006 to 2015, ED visits by infants and toddlers with anaphylaxis increased, whereas hospitalization of these patients decreased.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.