Evidence map›Paper›PMID 33485371›Full record

Trial reportJournal of neuroengineering and rehabilitation2021

Wearable vibrotactile stimulation for upper extremity rehabilitation in chronic stroke: clinical feasibility trial using the VTS Glove.

Caitlyn E Seim, Steven L Wolf, Thad E Starner

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07447934 (Vibrotactile Stimulation for Lower Limb Spasticity), which is not on this map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07447934 narecruitingnot on this mapstarted 2026, after this paper: background citation

Vibrotactile Stimulation for Lower Limb Spasticity

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2026 to 2027Enrolled25ConditionsLower Limb SpasticityArmsVibrotactile Stimulation (Static Use), Vibrotactile Stimulation (Dynamic Use), Vibrotactile Stimulation (Neurophysiological Mechanism)
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Interventions for perceptual disorders following stroke.The Cochrane database of systematic reviews · 2022
    Pooled it
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Artificial vibrotactile feedback elicits neural correlates of sense of agency.Journal of neuroengineering and rehabilitation · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Caitlyn E SeimDepartment of Mechanical Engineering, Stanford University, Stanford, CA, USA. cseim@stanford.edu.ORCID 0000-0002-4778-3212
Steven L WolfDepartment of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Thad E StarnerCollege of Computing, Georgia Institute of Technology, Atlanta, CA, USA.
Emory University · USGeorgia Institute of Technology · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluate the feasibility and potential impacts on hand function using a wearable stimulation device (the VTS Glove) which provides mechanical, vibratory input to the affected limb of chronic stroke survivors.

methodsA double-blind, randomized, controlled feasibility study including sixteen chronic stroke survivors (mean age: 54; 1-13 years post-stroke) with diminished movement and tactile perception in their affected hand. Participants were given a wearable device to take home and asked to wear it for three hours daily over eight weeks. The device intervention was either (1) the VTS Glove, which provided vibrotactile stimulation to the hand, or (2) an identical glove with vibration disabled. Participants were randomly assigned to each condition. Hand and arm function were measured weekly at home and in local physical therapy clinics.

resultsParticipants using the VTS Glove showed significantly improved Semmes-Weinstein monofilament exam results, reduction in Modified Ashworth measures in the fingers, and some increased voluntary finger flexion, elbow and shoulder range of motion.

conclusionsVibrotactile stimulation applied to the disabled limb may impact tactile perception, tone and spasticity, and voluntary range of motion. Wearable devices allow extended application and study of stimulation methods outside of a clinical setting.

Indexed as

Wearable Electronic DevicesAgedDouble-Blind MethodFeasibility StudiesFemaleHumansMaleMiddle AgedMuscle TonusPhysical Therapy ModalitiesRange of Motion, ArticularStroke RehabilitationTouch PerceptionUpper ExtremityVibrationSpasticityStimulationStrokeUpper extremityVibrotactile

Identifiers

PMID33485371
PMCPMC7824932
OpenAlexW3043722365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.