Evidence map›Paper›PMID 33485009›Full record

ArticleDrug and alcohol dependence2021

Staying or moving: Results of a latent transition analysis examining intra-individual stability of recreational substance use among MSM in the Multicenter AIDS Cohort Study from 2004 to 2016.

Syed W Noor, Trevor A Hart, Chukwuemeka N Okafor, Deanna Ware, Kara W Chew, Gypsyamber D'Souza, Ken Ho, M Reuel Friedman, Michael Plankey

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Syed W NoorDepartment of Psychology, Ryerson University, 350 Victoria Street, Toronto, ON, M5B 2K3, Canada; Department of Kinesiology and Health Science, Louisiana State University Shreveport, One University Place, Shreveport, LA, 71115, USA. Electronic address: swnoor@ryerson.ca.
Trevor A HartDepartment of Psychology, Ryerson University, 350 Victoria Street, Toronto, ON, M5B 2K3, Canada; Dalla Lana School of Public Health, University of Toronto, 155 College St Room 500, Toronto, ON M5T 3M7, Canada.
Chukwuemeka N OkaforDepartment of Public Health, Robbins College of Health and Human Sciences, Baylor University, 1311 S 5th St, Waco, TX, 76706, USA.
Deanna WareGeorgetown University Medical Center, Department of Medicine, 3800 Reservoir Road, NW PHC-5Washington, DC, 20007, USA.
Kara W ChewDavid Geffen School of Medicine at UCLA, 11075 Santa Monica Blvd, Suite 100, Los Angeles, CA, 90025, USA.
Gypsyamber D'SouzaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD, 21205, USA.
Ken HoDivision of Infectious Diseases, University of Pittsburgh, 3520 Fifth Avenue, Suite 533, Pittsburgh, PA, 15213, USA.
M Reuel FriedmanDepartment of Infectious Diseases and Microbiology, University of Pittsburgh, 130 De Soto St, Pittsburgh, PA, 15261, USA.
Michael PlankeyGeorgetown University Medical Center, Department of Medicine, 3800 Reservoir Road, NW PHC-5Washington, DC, 20007, USA.
Georgetown University · USUniversity of Pittsburgh · USBaylor University · USJohns Hopkins University · USLouisiana State University in Shreveport · USUniversity of California, Los Angeles · USUniversity of Toronto · CA

Funding

Multicenter Aids Cohort Study- Part B (Baltimore Site)U01AI035042 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T, MARGOLICK, JOSEPH B. · 1993 to 2018
$61.5M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Sex differences in the role of multi-omicsin HIV-associated carotid artery atherosclerosisU01HL146193 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Stephen J Gange, Elizabeth Topper · 2019 to 2026
$35.8M
Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC Center - Admin Supplement: Vision and dual sensory loss in HIV-infected older adultsU01HL146201 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Joseph B. Margolick · 2019 to 2026
$33.7M
University of Pittsburgh MWCCS Clinical Research SiteU01HL146208 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Bernard Jonas C Macatangay, CHARLES R RINALDO · 2019 to 2026
$32.2M
Study of Hearing and Balance in Middle Aged and Aging Men and Women in the MACS-WIHS Combined Cohort StudyU01HL146333 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Roger Detels, Matthew James Mimiaga · 2019 to 2026
$32.2M
Northwestern CORE Clinical Research Site: Trans-omics for HIV/AIDS ResearchU01HL146240 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Frank J Palella, Valentina Stosor · 2019 to 2026
$31.5M
Understanding Patterns of Healthy Aging among Men Who Have Sex with MenR01MD010680 · NIMHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRIEDMAN, MACKEY R, PLANKEY, MICHAEL W · 2015 to 2019
$2.9M
The impact of cannabinoids on inflammation, HIV viral load and symptoms of distress among persons living with HIVK01DA047912 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI OKAFOR, CHUKWUEMEKA NKEMAKONAM · 2019 to 2023
$682k
NHLBI NIH HHS U01 HL146193NHLBI NIH HHS U01 HL146201NHLBI NIH HHS U01 HL146208NHLBI NIH HHS U01 HL146240NHLBI NIH HHS U01 HL146333NIAID NIH HHS U01 AI035042NIDA NIH HHS K01 DA047912NIMHD NIH HHS R01 MD010680NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

backgroundStudies have examined patterns of substance use among Men who have Sex with Men (MSM), but few have examined factors predicting transitioning from one substance use pattern to another. We investigated transitioning from one substance use pattern to another over a 12-year period (2004-2016) among the Multicenter AIDS Cohort Study participants.

methodAlcohol, marijuana, heroin, cocaine, poppers, uppers (e.g., methamphetamines) and erectile dysfunction(ED) medications use in the last 6 months from 3568 US MSM was dichotomized (no/yes) to classify participants into substance use classes at each follow up visit. We fit latent transition models to calculate transition probabilities of moving from one substance use class to another over a 3, 4 and 6-year time period. Then fit regression models to identify factors associated with the probability of each participant staying in or moving from the same substance use class.

resultsOverall, cocaine and ED medication use declined but marijuana and heroin use increased over 2004-2016. We observed most participants (84.6 %-100 %) stayed in the same class. Increased age was associated with transition from the Minimal-use class to the Alcohol-only class (aOR = 1.06,95 %CI:1.01-1.13;p < 0.01) and non-White MSM reported lower odds of moving from the Alcohol-only class to the Alcohol-Popper class (aOR = 0.50,95 %CI:0.30-0.82;p <0.01). There were no difference in the transition probabilities by HIV-status.

conclusionDespite decline in substance use in general, participants are highly stable in their choice of substances. However, treating MSM as a homogeneous group can lead to an under-appreciation of the diversity of prevention needs and treatment of substance using MSM.

Indexed as

Latent Class AnalysisSexual and Gender MinoritiesAdultAlcohol DrinkingCohort StudiesHumansMaleMiddle AgedRecreational Drug UseUnited StatesLatent transition analysisLCAMACSMen who have sex with menSubstance use

Identifiers

PMID33485009
PMCPMC7901540
OpenAlexW3120329669

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.