Evidence map›Paper›PMID 33484966›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2021

METTL3 restrains papillary thyroid cancer progression via m

Jing He, Mingxia Zhou, Jie Yin, Junhu Wan, Jie Chu, Jinlin Jia, Jinxiu Sheng, Chang Wang, Huiqing Yin, Fucheng He

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 2 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 2 syntheses or guidelines pooled it, 187 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. mBiochemical genetics · 2026
    Article
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  9. Article
  10. Article
  11. WDR5-H3K4me3 Epigenetic Axis Promotes TRMT6-Dependent tRNA MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  17. Article
  18. Crosstalk between mFrontiers in immunology · 2026
    Review
  19. Review
  20. Article

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jing HeDepartment of Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Mingxia ZhouDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Jie YinDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Junhu WanDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Jie ChuDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Jinlin JiaDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Jinxiu ShengDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Chang WangDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Huiqing YinDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Fucheng HeDepartment of Medical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. Electronic address: hefucheng@zzu.edu.cn.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growing evidence indicates that N6-methyladenosine (m

Indexed as

Down-RegulationAdenosineAnimalsDisease ProgressionGene Expression ProfilingGene Expression Regulation, NeoplasticHumansInterleukin-8MaleMethyltransferasesMiceNeoplasm MetastasisNeoplasm TransplantationNeutrophil InfiltrationPrognosisProto-Oncogene Proteins c-relAdenosineCXCL8 protein, humanInterleukin-8MethyltransferasesMETTL3 protein, humanN-methyladenosineProto-Oncogene Proteins c-relREL protein, humanc-RelMETTL3N(6)-methyladenosineneutrophilspapillary thyroid cancerYTHDF2

Identifiers

PMID33484966
PMCPMC8116572
OpenAlexW3124070407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.