Evidence map›Paper›PMID 33484782›Full record

ArticleThe Journal of hospital infection2021

Containment of procedure-associated aerosols by an extractor tent: effect on nebulized drug particle dispersal.

M Fennelly, J Keane, L Dolan, B J Plant, D J O'Connor, J R Sodeau, M B Prentice

Open access · hybridAbstract read
In one paragraph

Article in The Journal of hospital infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Aerosol drug delivery to tracheotomized patients with COVID-19: Pragmatic suggestions for clinicians.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

M FennellyEnvironmental Research Institute, University College Cork, Cork, Ireland; Department of Pathology, University College Cork, Cork, Ireland. Electronic address: mehael.fennelly@umail.ucc.ie.
J KeaneRespiratory Assessment Unit, St. James's Hospital, Dublin, Ireland.
L DolanRespiratory Assessment Unit, St. James's Hospital, Dublin, Ireland.
B J PlantAdult Cystic Fibrosis Centre, Cork University Hospital, Cork, Ireland.
D J O'ConnorSchool of Chemical and Pharmaceutical Sciences, Technological University Dublin, Dublin, Ireland.
J R SodeauEnvironmental Research Institute, University College Cork, Cork, Ireland.
M B PrenticeDepartment of Pathology, University College Cork, Cork, Ireland; APC Microbiome Institute, University College Cork, Cork, Ireland. Electronic address: m.prentice@ucc.ie.
St. James's Hospital · IEUniversity College Cork · IEAPC Microbiome Institute · IECork University Hospital · IETechnological University Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral medical procedures involving the respiratory tract are considered as 'aerosol-generating procedures'. Aerosols from these procedures may be inhaled by bystanders, and there are consequent concerns regarding the transmission of infection or, specific to nebulized therapy, secondary drug exposure.

aimTo assess the efficacy of a proprietary high-efficiency-particulate-air-filtering extractor tent on reducing the aerosol dispersal of nebulized bronchodilator drugs.

methodsThe study was conducted in an unoccupied outpatient room at St. James's Hospital, Dublin, Ireland. A novel real-time, fluorescent particle counter, the Wideband Integrated Bioaerosol Sensor (WIBS), monitored room air continuously for 3 h. Baseline airborne particle count and count during nebulization of bronchodilator drug solutions were recorded.

findingsNebulization within the tent prevented any increase over background level. Nebulization directly into room air resulted in mean fluorescent particle counts of 4.75 x 10

conclusionThe extractor tent was completely effective for the prevention of airborne spread of drug particles of respirable size from nebulized therapy. This suggests that extractor tents of this type would be efficacious for the prevention of airborne infection from aerosol-generating procedures during the COVID-19 pandemic.

Indexed as

AdultAerosolsAgedAged, 80 and overAir FiltersCOVID-19Disease Transmission, InfectiousFemaleHumansIrelandMaleMiddle AgedNebulizers and VaporizersPandemicsParticulate MatterPractice Guidelines as TopicAerosolsParticulate MatterAirborneAir samplingContinuous monitoringCOVID-19EnvironmentNebulizerReal-time analysisWIBS

Identifiers

PMID33484782
PMCPMC7817412
OpenAlexW3122861759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.