ArticleCurrent biology : CB2021
Binocular integration of retinal motion information underlies optic flow processing by the cortex.
Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Ecological Visual Processing in the Mouse.Annual review of neuroscience · 2026Review
- Differential topographic organization and retinal inheritance of direction and orientation selectivity in the visual thalamus.Nature communications · 2025Article
- Direction-selective laterodorsal thalamic nucleus encodes optic flow and turning in spatial navigation.Neuron · 2025Article
- Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus.Neuron · 2025Article
- A competitive disinhibitory network for robust optic flow processing in Drosophila.Nature neuroscience · 2025Article
- Cortical circuits for cross-modal generalization.Nature communications · 2025Article
- Information-theoretic gradient flows in mouse visual cortex.Frontiers in neuroinformatics · 2025Article
- Neural mechanisms to incorporate visual counterevidence in self-movement estimation.Current biology : CB · 2023Article
- Neural mechanisms to incorporate visual counterevidence in self motion estimation.bioRxiv : the preprint server for biology · 2023Article
- Cortical Integration of Vestibular and Visual Cues for Navigation, Visual Processing, and Perception.Annual review of neuroscience · 2023Review
- Walking humans and running mice: perception and neural encoding of optic flow during self-motion.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Hierarchical and nonhierarchical features of the mouse visual cortical network.Nature communications · 2022Article
- A Hypothesis From Metabolomics Analysis of Diabetic Retinopathy: Arginine-Creatine Metabolic Pathway May Be a New Treatment Strategy for Diabetic Retinopathy.Frontiers in endocrinology · 2022Review
- Visuomotor control in mice and primates.Neuroscience and biobehavioral reviews · 2021Review
- EyeLoop: An Open-Source System for High-Speed, Closed-Loop Eye-Tracking.Frontiers in cellular neuroscience · 2021Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
Locomotion creates various patterns of optic flow on the retina, which provide the observer with information about their movement relative to the environment. However, it is unclear how these optic flow patterns are encoded by the cortex. Here, we use two-photon calcium imaging in awake mice to systematically map monocular and binocular responses to horizontal motion in four areas of the visual cortex. We find that neurons selective to translational or rotational optic flow are abundant in higher visual areas, whereas neurons suppressed by binocular motion are more common in the primary visual cortex. Disruption of retinal direction selectivity in Frmd7 mutant mice reduces the number of translation-selective neurons in the primary visual cortex and translation- and rotation-selective neurons as well as binocular direction-selective neurons in the rostrolateral and anterior visual cortex, blurring the functional distinction between primary and higher visual areas. Thus, optic flow representations in specific areas of the visual cortex rely on binocular integration of motion information from the retina.
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