Evidence map›Paper›PMID 33484426›Full record

Observational studyJournal of nephrology2021

Proteinuria in COVID-19: prevalence, characterization and prognostic role.

Justine Huart, Antoine Bouquegneau, Laurence Lutteri, Pauline Erpicum, Stéphanie Grosch, Guillaume Résimont, Patricia Wiesen, Christophe Bovy, Jean-Marie Krzesinski, Marie Thys and 8 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Journal of nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
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  6. The relation between proteinuria and the severity of COVID-19.Clinical and experimental nephrology · 2024
    Article
  7. COVID-19: a multi-organ perspective.Frontiers in cellular and infection microbiology · 2024
    Review
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  19. Urine sediment findings were milder in patients with COVID-19-associated renal injuries than in those with non-COVID-19-associated renal injuries.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Justine HuartDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium.
Antoine BouquegneauDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium.
Laurence LutteriDepartment of Clinical Chemistry, CHU Sart Tilman, University of Liège (CHU ULiege), Liège, Belgium.
Pauline ErpicumDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium.
Stéphanie GroschDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium.
Guillaume RésimontDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium.
Patricia WiesenDepartment of Intensive Care, CHU Sart Tilman, University of Liège (CHU ULiege), Liège, Belgium.
Christophe BovyDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium.
Jean-Marie KrzesinskiDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium.
Marie ThysDepartment of Medico-Economic Information, CHU Sart Tilman, University of Liège (CHU ULiege), Liège, Belgium.
Bernard LambermontDepartment of Intensive Care, CHU Sart Tilman, University of Liège (CHU ULiege), Liège, Belgium.
Benoît MissetDepartment of Intensive Care, CHU Sart Tilman, University of Liège (CHU ULiege), Liège, Belgium.
Hans PottelDepartment of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.
Christophe MariatNephrology, Dialysis and Renal Transplantation Department, Hôpital Nord, CHU de Saint-Etienne, Jean Monnet University, COMUE Université de Lyon, Lyon, France.
Etienne CavalierDepartment of Clinical Chemistry, CHU Sart Tilman, University of Liège (CHU ULiege), Liège, Belgium.
Stéphane BurteyCenter of Nephrology and Renal Transplantation, Public Assistance of the Hospitals of Marseille, Marseille, France.
François JouretDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium.ORCID http://orcid.org/0000-0003-2547-6593
Pierre DelanayeDepartment of Nephrology-Dialysis-Transplantation, Service de Dialyse, CHU Sart Tilman, University of Liège (CHU ULiege), 4000, Liège, Belgium. pierre_delanaye@yahoo.fr.ORCID http://orcid.org/0000-0002-1480-5761
University of Liège · BEInserm · FRKU Leuven · BEUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProteinuria has been commonly reported in patients with COVID-19. However, only dipstick tests have been frequently used thus far. Here, the quantification and characterization of proteinuria were investigated and their association with mortality was assessed.

methodsThis retrospective, observational, single center study included 153 patients, hospitalized with COVID-19 between March 28th and April 30th, 2020, in whom total proteinuria and urinary α

resultsAccording to the Kidney Disease Improving Global Outcomes staging, 14% (n = 21) of the patients had category 1 proteinuria (< 150 mg/g of urine creatinine), 42% (n = 64) had category 2 (between 150 and 500 mg/g) and 44% (n = 68) had category 3 proteinuria (over 500 mg/g). Urine α

conclusionsProteinuria is frequent in patients with COVID-19. Its characterization suggests a tubular origin, with increased urinary α

Indexed as

AgedAged, 80 and overBelgiumBiomarkersCOVID-19FemaleHumansMaleMiddle AgedPrevalencePrognosisProteinuriaRetrospective StudiesSurvival RateBiomarkersCOVID-19ProteinuriaTubular proteinuriaα1-microglobulin

Identifiers

PMID33484426
PMCPMC7823174
OpenAlexW3124957771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.