Evidence map›Paper›PMID 33484235›Full record

ArticlePhysiological reports2021

Computational and theoretical insights into the homeostatic response to the decreased cell size of midbrain dopamine neurons.

Francisco Arencibia-Albite, Carlos A Jiménez-Rivera

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Francisco Arencibia-AlbiteDepartment of Physiology, University of Puerto Rico, San Juan, Puerto Rico.ORCID 0000-0001-8087-5998
Carlos A Jiménez-RiveraDepartment of Physiology, University of Puerto Rico, San Juan, Puerto Rico.
University of Puerto Rico System · PR

Funding

PKMzeta involvement in cocaine sensitizationSC1GM084854 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI JIMENEZ-RIVERA, CARLOS A · 2008 to 2016
$2.4M
NIGMS NIH HHS 2SC1GM084854-05A1NIGMS NIH HHS SC1 GM084854
6 · The paper itself

Abstract

Midbrain dopamine neurons communicate signals of reward anticipation and attribution of salience. This capacity is distorted in heroin or cocaine abuse or in conditions such as human mania. A shared characteristic among rodent models of these behavioral disorders is that dopamine neurons in these animals acquired a small size and manifest an augmented spontaneous and burst activity. The biophysical mechanism underlying this increased excitation is currently unknown, but is believed to primarily follow from a substantial drop in K

Indexed as

Models, NeurologicalAction PotentialsAnimalsCell SizeComputational BiologyDopaminergic NeuronsElectrophysiological PhenomenaHomeostasisMesencephalonMiceMorphineNarcoticsMorphineNarcoticscapacitancecell sizecomputational modelingdopamine neurons

Identifiers

PMID33484235
PMCPMC7824968
OpenAlexW3124025005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.