Evidence map›Paper›PMID 33483797›Full record

ArticleEuropean journal of pediatrics2021

Metabolic syndrome and insulin resistance in pre-pubertal children with psoriasis.

Francesca Caroppo, Alfonso Galderisi, Laura Ventura, Anna Belloni Fortina

Open access · hybridAbstract read
In one paragraph

Article in European journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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  4. Role of acitretin in regulating glucose and lipid homeostasis in an imiquimod-induced psoriasis model mouse.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Francesca CaroppoPediatric Dermatology Unit - Department of Medicine DIMED, University of Padova, Via Gallucci, 4, 35128, Padova, Italy.ORCID http://orcid.org/0000-0003-3583-0816
Alfonso GalderisiDepartment of Woman and Child's Health, University of Padova, Padova, Italy.
Laura VenturaDepartment of Statistics, University of Padova, Padova, Italy.
Anna Belloni FortinaPediatric Dermatology Unit - Department of Medicine DIMED, University of Padova, Via Gallucci, 4, 35128, Padova, Italy. anna.bellonifortina@unipd.it.ORCID http://orcid.org/0000-0001-5791-0775
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis in adults is associated with an increased risk of metabolic disease. Various cardiometabolic comorbidities have been reported in childhood psoriasis, but only a few studies have analyzed the prevalence of metabolic syndrome. We performed a single-center prospective study investigating the prevalence of metabolic syndrome and insulin resistance in children with psoriasis. The prevalence of metabolic syndrome was evaluated in 60 pre-pubertal children with psoriasis (age: 3-10 years), accordingly to recently established criteria for the diagnosis of metabolic syndrome in children. Insulin resistance was considered altered when the homeostatic model assessment (HOMA-IR) for insulin resistance was ≥ 90th sex- and age-specific percentile and HOMA 2-IR was > 1.8. Eighteen (30%) children with psoriasis were found to have metabolic syndrome. Sixteen (27%) children were found to have insulin resistance.Conclusion: Our data underline the importance of assessing metabolic syndrome not only in adults and adolescents but also in young children with psoriasis. What is Known: • Psoriasis in adults is strongly associated with metabolic disease and insulin resistance. • Very limited data are available on the prevalence of metabolic syndrome and insulin resistance in pre-pubertal children with psoriasis. What is New: • This study reports that in pre-pubertal children with psoriasis, there is a high prevalence of metabolic syndrome and insulin resistance. • In children with psoriasis metabolic syndrome risk factors should be assessed.

Indexed as

Insulin ResistanceMetabolic SyndromePsoriasisAdolescentAdultBody Mass IndexChildChild, PreschoolHumansInsulinProspective StudiesRisk FactorsInsulinChildhood psoriasisHOMA-IRInsulin resistanceMetabolic syndromePediatric psoriasisPsoriasis

Identifiers

PMID33483797
PMCPMC8105196
OpenAlexW3122878625

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.