Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
Cancer pain management in the emergency department: a multicenter prospective observational trial of the Comprehensive Oncologic Emergencies Research Network (CONCERN).
Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Understanding oncologic emergencies and related emergency department visits and hospitalizations: a systematic review.BMC emergency medicine · 2025Pooled it
- Smart Dosing, Better Outcomes: An Electronic Medical Record Intervention for Cancer Pain in the Emergency Department.Journal of the American College of Emergency Physicians open · 2026Article
- Pain Disparities Among Asian Americans Affected by Cancer: The Role of Depressive Symptoms.Journal of palliative medicine · 2026Article
- Characteristics associated with accepting hospital at home among patients with cancer and their caregivers: a cross-sectional survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Trends of opioids consumption for cancer patients treated by the palliative care department at the last week of life in a tertiary care center.BMC palliative care · 2025Article
- Parents' Experiences and Clinicians' Perceptions of Managing Cancer Pain in Young Children at Home.Current oncology (Toronto, Ont.) · 2025Article
- Epidemiologic trends and characteristics of cancer-related emergency department visits of older patients living with cancer in South Korea.Scientific reports · 2025Observational
- Epidemiology of Non-Emergent Cancer-Related Emergency Department Visits in Korea between 2016 and 2020.Yonsei medical journal · 2024Article
- Immune-related adverse event in the emergency department: methodology of the immune-related emergency disposition index (IrEDi).Emergency cancer care · 2024Article
- Pain Management at the End of Life in the Emergency Department: A Narrative Review of the Literature and a Practical Clinical Approach.Journal of clinical medicine · 2023Review
- Benefits of Spiritual and Religious Support in the Pain Management of Cancer Patients: A Literature Scoping Review.Journal of religion and health · 2023Article
- Effect of Fu's subcutaneous needling for cancer pain management: protocol for a pragmatic randomised controlled trial.BMJ open · 2023Article
- Fentanyl in cancer pain management: avoiding hasty judgments and discerning its potential benefits.Drugs in context · 2023Review
- Characteristics and Outcomes of Patients with Cancer Pain Placed in an Emergency Department Observation Unit.Cancers · 2022Article
- Psychological Evaluation of Patients With Cancer Presenting to the Emergency Department With Pain: Independent Predictors of Worse Pain Severity, Interference, and Higher Hourly Opioid Administration.JCO oncology practice · 2022Article
- Different Machine Learning Approaches for Implementing Telehealth-Based Cancer Pain Management Strategies.Journal of clinical medicine · 2022Article
- Characterization of older adults with cancer seeking acute emergency department care: A prospective observational study.Journal of geriatric oncology · 2022Observational
- Approach to Cancer Pain Management in Emergency Departments: Comparison of General and Oncology Based Settings.Pharmaceuticals (Basel, Switzerland) · 2022Article
- The Value Proposition of Observation Medicine in Managing Acute Oncologic Pain.Current oncology reports · 2022Review
- Outcomes of Patients Placed in an Emergency Department Observation Unit of a Comprehensive Cancer Center.JCO oncology practice · 2022Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMany patients with cancer seek care for pain in the emergency department (ED). Prospective research on cancer pain in this setting has historically been insufficient. We conducted this study to describe the reported pain among cancer patients presenting to the ED, how pain is managed, and how pain may be associated with clinical outcomes.
methodsWe conducted a multicenter cohort study on adult patients with active cancer presenting to 18 EDs in the USA. We reported pain scores, response to medication, and analgesic utilization. We estimated the associations between pain severity, medication utilization, and the following outcomes: 30-day mortality, 30-day hospital readmission, and ED disposition.
resultsThe study population included 1075 participants. Those who received an opioid in the ED were more likely to be admitted to the hospital and were more likely to be readmitted within 30 days (OR 1.4 (95% CI: 1.11, 1.88) and OR 1.56 (95% CI: 1.17, 2.07)), respectively. Severe pain at ED presentation was associated with increased 30-day mortality (OR 2.30, 95% CI: 1.05, 5.02), though this risk was attenuated when adjusting for clinical factors (most notably functional status).
conclusionsPatients with severe pain had a higher risk of mortality, which was attenuated when correcting for clinical characteristics. Those patients who required opioid analgesics in the ED were more likely to require admission and were more at risk of 30-day hospital readmission. Future efforts should focus on these at-risk groups, who may benefit from additional services including palliative care, hospice, or home-health services.
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Registered trials
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