Evidence map›Paper›PMID 33483778›Full record

ArticleAbdominal radiology (New York)2021

Comparative study of evaluating the microcirculatory function status of primary small HCC between the CE (DCE-MRI) and Non-CE (IVIM-DWI) MR Perfusion Imaging.

Qiong Song, Yixian Guo, Xiuzhong Yao, Shengxiang Rao, Chengyao Qian, Dexian Ye, Mengsu Zeng

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Article in Abdominal radiology (New York), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qiong SongDepartment of Radiology, Zhongshan Hospital of Fudan University, Fudan University, Shanghai Institute of Medical Imaging, No 130, Dongan Rd, Xuhui District, Shanghai, 200032, People's Republic of China.
Yixian GuoDepartment of Radiology, Zhongshan Hospital of Fudan University, Fudan University, Shanghai Institute of Medical Imaging, No 130, Dongan Rd, Xuhui District, Shanghai, 200032, People's Republic of China.ORCID http://orcid.org/0000-0002-9247-6684
Xiuzhong YaoDepartment of Radiology, Zhongshan Hospital of Fudan University, Fudan University, Shanghai Institute of Medical Imaging, No 130, Dongan Rd, Xuhui District, Shanghai, 200032, People's Republic of China.ORCID http://orcid.org/0000-0003-3234-7511
Shengxiang RaoDepartment of Radiology, Zhongshan Hospital of Fudan University, Fudan University, Shanghai Institute of Medical Imaging, No 130, Dongan Rd, Xuhui District, Shanghai, 200032, People's Republic of China.
Chengyao QianShanghai Aitrox Technology Corporation Limited, Shanghai, 200032, People's Republic of China.
Dexian YeShanghai Aitrox Technology Corporation Limited, Shanghai, 200032, People's Republic of China.
Mengsu ZengDepartment of Radiology, Zhongshan Hospital of Fudan University, Fudan University, Shanghai Institute of Medical Imaging, No 130, Dongan Rd, Xuhui District, Shanghai, 200032, People's Republic of China. zeng.mengsu@zs-hospital.sh.cn.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the difference of evaluating the microcirculatory function status of primary small HCC between DCE-MRI with two-compartmental pharmacokinetic model and IVIM-DWI.

methods27 patients (22 men, 5 women; mean age, 49 years; range 36-65 years) with primary single sHCC who underwent IVIM-DWI and DCE-MRI before the operation were included in this retrospective study. The MR perfusion parameters are Ktrans, Ve, Kep, D, D* and f. Pathological results include pathological grade (low grade ≤ II, high grade > II) and MVD. The perfusion parameters and pathological results of sHCC were analyzed and compared in their relevance, sensitivity and specificity. Statistical methods included Spearman and ROC curve analysis.

resultsThe perfusion parameters (Ktrans, Kep, D*, f) were significantly positive correlated (r = 0.892, 0.808, 0.589 and 0.543, P = 0.000, 0.000, 0.001 and 0.003 with MVD of sHCC. The parameter Ve and D values were negatively correlated (r = - 0.454 and - 0.399, P = 0.017 and 0.039, respectively) with the pathological grade. Regarding the evaluation MVD of sHCC, the evaluation of the sensitivity and specificity performance was present in descending order: Ktrans > Kep > PF > D*. In the evaluation pathological grade of sHCC, the sensitivity and specificity were better by parameters D than Ve.

conclusionDCE-MRI is better than IVIM-DWI for evaluation microcirculation functional status of sHCC. But for evaluating the pathological grade, IVIM-DWI is better than DCE-MRI. Combination of the two imaging techniques may provide more comprehensive evaluation in microcirculation functional status of the sHCC.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAdultAgedContrast MediaDiffusion Magnetic Resonance ImagingFemaleHumansMagnetic Resonance ImagingMaleMicrocirculationMiddle AgedPerfusionPerfusion ImagingRetrospective StudiesContrast MediaDynamic contrast-enhancedHepatocellular carcinomaIntravoxel incoherent motionMicrocirculationMR perfusion imaging

Identifiers

PMID33483778
OpenAlexW3123704692

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.