ReviewNature reviews. Neuroscience2021
The default mode network: where the idiosyncratic self meets the shared social world.
Review in Nature reviews. Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 306 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
306 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Together we sync: a systematic qualitative and quantitative review of fMRI hyperscanning studies.Social cognitive and affective neuroscience · 2026Pooled it
- PTSD subtypes and their underlying neural biomarkers: a systematic review.Psychological medicine · 2025Pooled it
- The research progress on effective connectivity in adolescent depression based on resting-state fMRI.Frontiers in neurology · 2025Pooled it
- The science of story characters: a neuroimaging perspective on antagonists in narrative engagement.Frontiers in human neuroscience · 2025Pooled it
- Brain functional basis of the association between positive expectation and acupuncture efficacy in knee osteoarthritis.Brain imaging and behavior · 2026Trial
- Examining emotion reactivity to politically polarizing media in a randomized controlled trial of mindfulness training versus active coping training.Scientific reports · 2025Trial
- Reward sensitivity is negatively associated with future self-continuity: the mediation role of functional connectivity between the dorsomedial prefrontal cortex and ventrolateral prefrontal cortex.Brain structure & function · 2026Article
- Medial temporal default mode network selectively encodes autobiographical visual imagery.Science advances · 2026Article
- Retinotopic coding organizes the interaction between internally and externally oriented brain networks.eLife · 2026Article
- Adolescent exposure to the psychedelic 25C-NBOMe in rats induces lasting competitive avoidance through disrupted hippocampal-prefrontal synchrony.Nature neuroscience · 2026Article
- Narrative coherence shapes functional connectivity in default mode and frontoparietal networks.Neuroimage. Reports · 2026Article
- Music evokes shared neural representations of imagined narratives across sensory modalities.Nature communications · 2026Article
- Resting-state local brain functional synchronization after a single trigger-zone stimulation: with versus without evoked pain in classical trigeminal neuralgia patients.The journal of headache and pain · 2026Article
- Human brain-wide activation of sleep rhythms.eLife · 2026Article
- Towards naturalistic social neuroscience: A multi-level framework integrating real-world phenotyping, neurobiology, and computational mechanisms.Cognitive, affective & behavioral neuroscience · 2026Review
- Hierarchical neural integration of musical structure during expert performance.bioRxiv : the preprint server for biology · 2026Article
- Shared memories of event details in the human brain are altered by misinformation and test expectations.PLoS biology · 2026Article
- Meta-awareness, mind-wandering, and the control of automatic external and internal orientations of attention.Communications biology · 2026Article
- Non-duality in brain and experience of advanced meditators-key role for intrinsic neural timescales.Communications biology · 2026Article
- Embodied Neuropsychodynamics of the Relational Self Across Space and Time: An Integrative Narrative Review.Brain sciences · 2026Review
246 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The default mode network (DMN) is classically considered an 'intrinsic' system, specializing in internally oriented cognitive processes such as daydreaming, reminiscing and future planning. In this Perspective, we suggest that the DMN is an active and dynamic 'sense-making' network that integrates incoming extrinsic information with prior intrinsic information to form rich, context-dependent models of situations as they unfold over time. We review studies that relied on naturalistic stimuli, such as stories and movies, to demonstrate how an individual's DMN neural responses are influenced both by external information accumulated as events unfold over time and by the individual's idiosyncratic past memories and knowledge. The integration of extrinsic and intrinsic information over long timescales provides a space for negotiating a shared neural code, which is necessary for establishing shared meaning, shared communication tools, shared narratives and, above all, shared communities and social networks.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.