Evidence map›Paper›PMID 33483600›Full record

ArticleNPJ precision oncology2021

Synergistic activation of mutant TERT promoter by Sp1 and GABPA in BRAF

Yongxing Wu, Liang Shi, Yuelei Zhao, Pu Chen, Rongrong Cui, Meiju Ji, Nongyue He, Maode Wang, Gang Li, Peng Hou

Open access · goldAbstract read
In one paragraph

Article in NPJ precision oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
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  7. Article
  8. Article
  9. Article
  10. Blocking interplay between TERT and c-Myc: a new therapeutic strategy forInternational journal of biological sciences · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Role of post-translational modifications of Sp1 in cancer: state of the art.Frontiers in cell and developmental biology · 2024
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yongxing WuKey Laboratory for Tumor Precision Medicine of Shaanxi Province and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, People's Republic of China.
Liang ShiKey Laboratory for Tumor Precision Medicine of Shaanxi Province and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, People's Republic of China.
Yuelei ZhaoKey Laboratory for Tumor Precision Medicine of Shaanxi Province and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, People's Republic of China.
Pu ChenKey Laboratory for Tumor Precision Medicine of Shaanxi Province and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, People's Republic of China.
Rongrong CuiKey Laboratory for Tumor Precision Medicine of Shaanxi Province and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, People's Republic of China.
Meiju JiCenter for Translational Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, People's Republic of China.
Nongyue HeState Key Laboratory of Bioelectronics, Southeast University, 210096, Nanjing, People's Republic of China.
Maode WangDepartment of Neurosurgery, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, People's Republic of China. maodewang@163.com.
Gang LiDepartment of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, 710038, Xi'an, People's Republic of China. liliangxbyt@aliyun.com.
Peng HouKey Laboratory for Tumor Precision Medicine of Shaanxi Province and Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University, 710061, Xi'an, People's Republic of China. phou@xjtu.edu.cn.
First Affiliated Hospital of Xi'an Jiaotong University · CNAir Force Medical University · CNState Key Laboratory of Digital Medical Engineering

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activating TERT promoter mutations and BRAF

Identifiers

PMID33483600
PMCPMC7822828
OpenAlexW3122583534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.