Evidence map›Paper›PMID 33483566›Full record

ArticleScientific reports2021

Respiratory tract infections in children with allergic asthma on allergen immunotherapy during influenza season.

Yuyun Li, Dongming Wang, Lili Zhi, Yunmei Zhu, Lan Qiao, Yan Zhu, Xin Hu, Qian Wang, Yuan Cao, Yan Gao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Yuyun LiZibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Dongming WangPeople's Hospital of Huantai County, No. 2198, Huantai Street, Zibo City, 256400, Shandong Province, China.
Lili ZhiZibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China. zbzxyygmk@163.com.
Yunmei ZhuZibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Lan QiaoZibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Yan ZhuZibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Xin HuZibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Qian WangZibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Yuan CaoZibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Yan GaoZhangdian District Center for Disease Control and Prevention, No. 184, Xincun West Road, Zibo, 255000, Shandong Province, China.
Yousheng ChenRespiratory Medicine Department, Zibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Zeng ZhangDepartment of ENT, Zibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Fangjie BiInternal Cardiovascular Department, Zibo Central Hospital, No. 54, Gongqingtuan West Road, Zibo, 255036, Shandong Province, People's Republic of China.
Guangxing YanPediatrics, Zibo Municipal Hospital, No. 139, Huangong Road, Zibo, 255400, Shandong Province, China.
Central Hospital of Zibo · CNShandong Center for Disease Control and Prevention · CNShandong First Medical University · CNXintai People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To describle how respiratory tract infections (RTIs) that occurred in children with allergic asthma (AA) on allergen immunotherapy (AIT) during an influenza season. Data including clinical symptoms and treatment history of children (those with AA on AIT and their siblings under 14 years old), who suffered from RTIs during an influenza season (Dec 1st, 2019-Dec 31st, 2019), were collected (by face to face interview and medical records) and analyzed. Children on AIT were divided into 2 groups: stage 1 (dose increasing stage) and stage 2 (dose maintenance stage). Their siblings were enrolled as control. During the study period, 49 children with AA on AIT (33 patients in stage 1 and 16 patients in stage 2) as well as 49 children without AA ( their siblings ) were included. There were no significant differences in occurrences of RTIs among the three groups (p > 0.05). Compared with children in the other two groups, patients with RTIs in stage 2 had less duration of coughing and needed less medicine. Children on AIT with maintenance doses had fewer symptoms and recovered quickly when they were attacked by RTIs, which suggested that AIT with dose maintenance may enhance disease resistance of the body.

Indexed as

ImmunotherapySeasonsAdolescentAllergensAnimalsAsthmaCase-Control StudiesChildDose-Response Relationship, ImmunologicFemaleHumansHypersensitivityInfluenza, HumanMalePyroglyphidaeRespiratory Tract InfectionsAllergens

Identifiers

PMID33483566
PMCPMC7822879
OpenAlexW3122833635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.