Evidence map›Paper›PMID 33483485›Full record

ArticleNPJ schizophrenia2021

Negative symptoms and speech pauses in youths at clinical high risk for psychosis.

Emma R Stanislawski, Zarina R Bilgrami, Cansu Sarac, Sahil Garg, Stephen Heisig, Guillermo A Cecchi, Carla Agurto, Cheryl M Corcoran

Open access · goldAbstract read
In one paragraph

Article in NPJ schizophrenia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Emma R StanislawskiIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Zarina R BilgramiIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Cansu SaracIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-3819-5918
Sahil GargIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Stephen HeisigIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Guillermo A CecchiIBM T.J. Watson Research Center, Yorktown Heights, NY, USA.ORCID http://orcid.org/0000-0003-1013-8348
Carla AgurtoIBM T.J. Watson Research Center, Yorktown Heights, NY, USA.
Cheryl M CorcoranIcahn School of Medicine at Mount Sinai, New York, NY, USA. Cheryl.corcoran@mssm.edu.ORCID http://orcid.org/0000-0002-8902-4353
Icahn School of Medicine at Mount Sinai · USIBM Research - Thomas J. Watson Research Center · USJames J. Peters VA Medical Center · US

Funding

Thought disorder and social cognition in clinical risk states for schizophreniaR01MH107558 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI CORCORAN, CHERYL MARY · 2016 to 2020
$3.3M
Using the RDoC Approach to Understand Thought Disorder: A Linguistic Corpus-Based ApproachR01MH115332 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CORCORAN, CHERYL MARY · 2018 to 2020
$1.6M
NIMH NIH HHS R01 MH107558NIMH NIH HHS R01 MH115332
6 · The paper itself

Abstract

Aberrant pauses are characteristic of schizophrenia and are robustly associated with its negative symptoms. Here, we found that pause behavior was associated with negative symptoms in individuals at clinical high risk (CHR) for psychosis, and with measures of syntactic complexity-phrase length and usage of determiners that introduce clauses-that we previously showed in this same CHR cohort to help comprise a classifier that predicted psychosis. These findings suggest a common impairment in discourse planning and verbal self-monitoring that affects both speech and language, and which is detected in clinical ratings of negative symptoms.

Identifiers

PMID33483485
PMCPMC7822906
OpenAlexW3126044905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.