Evidence map›Paper›PMID 33483374›Full record

ArticleCancer research2021

Konstantinos V Floros, JinYang Cai, Sheeba Jacob, Richard Kurupi, Carter K Fairchild, Mayuri Shende, Colin M Coon, Krista M Powell, Benjamin R Belvin, Bin Hu and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 146 citations in OpenAlex.

  1. Article
  2. Targeted extracellular degradation of LRP8 promotes ferroptosis in cancer cells.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. The Emerging Role of Ferroptosis in Pediatric Cancer Biology and Therapy.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Decoding ferroptosis for cancer therapy.Nature reviews. Cancer · 2025
    Review
  18. Review
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Konstantinos V Floros *School of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.ORCID 0000-0003-4916-2257
JinYang Cai *School of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.
Sheeba Jacob *School of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.
Richard KurupiSchool of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.
Carter K FairchildSchool of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.
Mayuri ShendeDepartment of Pathology, Virginia Commonwealth University and Massey Cancer Center, Richmond, Virginia.
Colin M CoonSchool of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.
Krista M PowellSchool of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.
Benjamin R BelvinSchool of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.
Bin HuDepartment of Pathology, Virginia Commonwealth University and Massey Cancer Center, Richmond, Virginia.
Madhavi PuchalapalliDepartment of Pathology, Virginia Commonwealth University and Massey Cancer Center, Richmond, Virginia.
Sivapriya RamamoorthyDiscovery and Translational Sciences, Metabolon Inc., Research Triangle Park, North Carolina.
Kimberly SwiftDiscovery and Translational Sciences, Metabolon Inc., Research Triangle Park, North Carolina.
Janina P LewisSchool of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia.
Mikhail G DozmorovDepartment of Biostatistics, Virginia Commonwealth University, Richmond, Virginia.ORCID 0000-0002-0086-8358
John GlodNational Cancer Institute Pediatric Oncology Branch, Bethesda, Maryland.
Jennifer E KoblinskiDepartment of Pathology, Virginia Commonwealth University and Massey Cancer Center, Richmond, Virginia.ORCID 0000-0002-7156-2030
Sosipatros A BoikosDivision of Hematology, Oncology and Palliative Care, Virginia Commonwealth University and Massey Cancer Center, Richmond, Virginia.
Anthony C FaberSchool of Dentistry, VCU Philips Institute and Massey Cancer Center, Richmond, Virginia. acfaber@vcu.edu.
Virginia Cancer Institute · USVirginia Commonwealth University · USResearch Triangle Park Foundation · USNational Cancer Institute · US

Funding

Pediatric Oncology Branch Clinical Care and EducationZIEBC011516 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GLOD, JOHN · 2013 to 2025
$69.1M
Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Keri R Maher · 1985 to 2026
$51.0M
ABT-199 based therapies to treat neuroblastomaR01CA215610 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Anthony Charles Faber · 2017 to 2026
$2.9M
Intramural NIH HHS ZIE BC011516NCI NIH HHS P30 CA016059NCI NIH HHS R01 CA215610
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntioxidantsAuranofinCell Line, TumorCell ProliferationCell SurvivalChildEnzyme InhibitorsFerroptosisGene AmplificationGene Expression Regulation, EnzymologicGlutathioneHumansIronMaleMice(4-(bis(4-chlorophenyl)methyl)-1-piperazinyl)(5-methyl-4-nitro-1,2-oxazol-3-yl)methanoneAntioxidantsAuranofinEnzyme InhibitorsGlutathioneIronMYCN protein, humanN-Myc Proto-Oncogene ProteinOxazolesPhospholipid Hydroperoxide Glutathione PeroxidasePiperazinesSulfasalazine

Identifiers

PMID33483374
PMCPMC9281612
OpenAlexW3122079295

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.