Evidence map›Paper›PMID 33482892›Full record

ArticleGenome biology2021

tidybulk: an R tidy framework for modular transcriptomic data analysis.

Stefano Mangiola, Ramyar Molania, Ruining Dong, Maria A Doyle, Anthony T Papenfuss

Abstract read
In one paragraph

Article in Genome biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Efficient and Tidy Manipulation of Annotated Matrix Data with plyxp.bioRxiv : the preprint server for biology · 2026
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  12. ThebioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. Transcriptional signature of CD56Frontiers in immunology · 2024
    Article
  15. Article
  16. Article
  17. sccomp: Robust differential composition and variability analysis for single-cell data.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Taurine deficiency as a driver of aging.Science (New York, N.Y.) · 2023
    Article
  19. Article
  20. Pathogens (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefano MangiolaBioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Ramyar MolaniaBioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Ruining DongBioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Maria A DoylePeter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.
Anthony T PapenfussBioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia. papenfuss@wehi.edu.au.ORCID 0000-0002-1102-8506

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, efforts have been made toward the harmonization of transcriptomic data structures and workflows using the concept of data tidiness, to facilitate modularisation. We present tidybulk, a modular framework for bulk transcriptional analyses that introduces a tidy transcriptomic data structure paradigm and analysis grammar. Tidybulk covers a wide variety of analysis procedures and integrates a large ecosystem of publicly available analysis algorithms under a common framework. Tidybulk decreases coding burden, facilitates reproducibility, increases efficiency for expert users, lowers the learning curve for inexperienced users, and bridges transcriptional data analysis with the tidyverse. Tidybulk is available at R/Bioconductor bioconductor.org/packages/tidybulk .

Indexed as

Data AnalysisTranscriptomeAlgorithmsComputational BiologyEcosystemGene Expression ProfilingGenomicsReproducibility of ResultsSoftware

Identifiers

PMID33482892
PMCPMC7821481

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.