Trial reportBMC oral health2021
Effect of a 980-nm diode laser on post-operative pain after endodontic treatment in teeth with apical periodontitis: a randomized clinical trial.
Trial report in BMC oral health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04486196 (Effect of Root Canal Disinfection With 980 µm Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis), which is not on this map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Root Canal Disinfection With 980 µm Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis: A Randomized Clinical Trial
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Clinical Efficiency of Lasers in Endodontic Treatment of Primary Endodontic Cases: An Umbrella Review of Systematic Reviews.International dental journal · 2026Pooled it
- Analgesic Efficacy of Low-Level Laser Therapy for Postoperative Endodontic Pain: A Systematic Review and Meta-Analysis.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Pooled it
- Postoperative pain in primary root canal treatments after Er: YAG laser-activated irrigation: a systematic review and meta-analysis.Lasers in medical science · 2025Pooled it
- Lasers efficacy in pain management after primary and secondary endodontic treatment: a systematic review and meta-analysis of randomized clinical trials.Scientific reports · 2024Pooled it
- Preventive and therapeutic effects of semiconductor laser on pain in root canal treatment.European journal of medical research · 2025Trial
- Effect of intracanal cryotherapy on post-operative pain in single-visit endodontic retreatment: a randomized clinical trial.BMC oral health · 2024Trial
- The efficacy of 2780 nm Er,Cr;YSGG and 940 nm Diode Laser in root canal disinfection: A randomized clinical trial.Clinical oral investigations · 2024Trial
- Adjuvant therapy with a 980-nm diode laser in root canal retreatment: randomized clinical trial with 1-year follow-up.Lasers in medical science · 2023Trial
- The effect of different irrigation and disinfection methods on post-operative pain in mandibular molars: a randomised clinical trial.BMC oral health · 2022Trial
- Determining the optimal irrigation activation or agitation techniques for postoperative pain control: A network meta-regression of clinical trials.The Japanese dental science review · 2026Review
- Efficacy of diode Laser compared to conventional irrigation in endodontic treatment of apical periodontitis: a systematic review and meta-analysis.Frontiers in oral health · 2026Review
- Laser Therapy in the Management of Endodontic-Periodontal Lesions: A Comprehensive Review of Clinical Efficacy and Therapeutic Applications.Journal of lasers in medical sciences · 2026Review
- Article
- Depth-Resolved OCT of Root Canal Walls After Diode-Laser Irradiation: A Descriptive Ex Vivo Study Following a Stereomicroscopy Report.Diagnostics (Basel, Switzerland) · 2025Article
- Diode Laser-Guided Protocol for Endo-Perio Lesions: Toward a Multi-Stage Therapeutic Strategy-A Case Series and Brief Literature Review.Medicina (Kaunas, Lithuania) · 2025Review
- Article
- Effectiveness of Irrigation Protocols in Endodontic Therapy: An Umbrella Review.Dentistry journal · 2025Review
- Non-surgical Management of a Large Endodontic Lesion Using Diode Laser-Assisted Decompression and Photobiomodulation Therapy: A Case Report.Journal of lasers in medical sciences · 2025Article
- Article
- A 980 nm Diode Laser as an Adjunctive Therapy on the Healing of Apical Periodontitis Following Endodontic Retreatment: A Randomized Controlled Clinical Trial Study.Journal of lasers in medical sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to assess the effect of a 980-nm diode laser following chemomechanical root canal preparation on the severity of post-operative pain (PP) after root canal treatment (RCT).
methodsThis study included asymptomatic, single-rooted teeth with a periapical index (PAI) score of 3 or 4. All the patients received RCT, including dressing with calcium hydroxide (Ca(OH)
resultsThe average pain level in the control group 24 h after the first visit was significantly higher than that in the laser group (p < 0.05). The average pain level 24 h and 48 h after the second visit was significantly higher in the control group (p < 0.05). The levels of PP 24 h after the first visit were higher than those after the second visit only in the control group (p < 0.05). After the first visit, analgesic use in the control group was significantly higher after 8 h (40%) and 24 h (23%) as compared with that in the laser group (p < 0.05).
conclusionsRoot canal irradiation with a diode laser may reduce PP after RCT in single-rooted teeth with a PAI score of 3 or 4.
trial registrationEffect of the Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth with Apical Periodontitis: NCT04486196. Registered 24 July 2020-Retrospectively registered, http://clinicaltrials.gov/ct2/show/NCT04486196.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.