Evidence map›Paper›PMID 33482760›Full record

ArticleBMC pregnancy and childbirth2021

Risk factors and comorbidities associated with magnesium deficiency in pregnant women and women with hormone-related conditions: analysis of a large real-world dataset.

Svetlana Orlova, Galina Dikke, Gisele Pickering, Natalya Yaltseva, Sofya Konchits, Kirill Starostin, Alina Bevz

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Svetlana OrlovaDepartment of Dietetics and Clinical Nutritiology of Continuing Medical Education, Medical Institute, RUDN University, Moscow, Russia.
Galina DikkeDepartment of Obstetrics and Gynecology with a course of Reproductive Medicine, The Academy of Medical Education. F.I. Inozemtsev, Saint-Petersburg, Russia.
Gisele PickeringDepartment of Clinical Pharmacology Inserm CIC 1405, University Hospital, Clermont-Ferrand, France.
Natalya YaltsevaDepartment of General Medicine, The Yaroslavl State Medical University Institute of Postgraduate Education, Yaroslavl, Russia.
Sofya KonchitsDepartment of Medical Affairs, Sanofi, Moscow, Russia.
Kirill StarostinDepartment of Medical Affairs, Sanofi, Moscow, Russia. Kirill.Starostin@sanofi.com.ORCID http://orcid.org/0000-0001-6488-7980
Alina BevzDepartment of Medical Affairs, Sanofi, Moscow, Russia.
Inserm · FRPeoples' Friendship University of Russia · RUSanofi (France) · FR

Funding

Sanofi N/A
6 · The paper itself

Abstract

backgroundAn accumulating body of literature indicates that magnesium deficiency is associated with a number of hormone-related conditions (HRC) in women, and epidemiological studies are needed to assess its prevalence and risk factors. Here, we present a secondary analysis of data pooled from four large observational studies that assessed magnesium deficiency among pregnant women and women with HRC across the Russian Federation.

methodsThe main objective of this analysis was to estimate the prevalence of magnesium deficiency in this population and to describe risk factors and comorbidities associated with low serum magnesium. Univariate logistic regression analysis was performed to identify the risk factors and comorbid conditions associated with an increased risk of low serum magnesium level.

resultsA total of 983 pregnant women and 9444 women with HRC were eligible for analysis. Prevalence of hypomagnesemia (magnesium serum level cut-off < 0.66 mmol/L/< 0.8 mmol/L) was 34.0%/78.9% in pregnant women and 21.4%/54.8% in women with HRC. The highest prevalence of magnesium deficiency was observed for osteoporosis and climacteric syndrome. Risk factors included diastolic blood pressure, previous pregnancy complications, infections and edema for pregnant women, and age, body mass index, and various comorbidities for women with HRC.

conclusionsThese results confirm the high prevalence of hypomagnesemia in pregnant women and women with HRC and underline the importance of routine screening, since risk factors are mostly non-specific.

Indexed as

AdultComorbidityEndocrine System DiseasesFemaleHumansLogistic ModelsMagnesium DeficiencyMass ScreeningMiddle AgedPregnancyPregnancy ComplicationsRisk AssessmentRisk FactorsRussiaClimacteric syndromeHormone replacement therapyMagnesium deficiencyOral contraceptivesOsteoporosisPregnancy

Identifiers

PMID33482760
PMCPMC7821493
OpenAlexW3120039162

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.