ArticleBMC infectious diseases2021
Epidemiological survey and screening strategy for dengue virus in blood donors from Yunnan Province.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Two-Year Surveillance of Dengue, Zika, and Chikungunya Viruses Among Chinese Blood Donors - Guangxi and Yunnan PLADs, China, 2022-2023.China CDC weekly · 2025Article
- Occupational exposure to malaria, leishmaniasis and arbovirus vectors in endemic regions: A systematic review.Current research in parasitology & vector-borne diseases · 2024Review
- Estimating Dengue Transmission Intensity in China Using Catalytic Models Based on Serological Data.Tropical medicine and infectious disease · 2023Article
- Retrospective investigation of the origin and epidemiology of the dengue outbreak in Yunnan, China from 2017 to 2018.Frontiers in veterinary science · 2023Article
- Assessment of dengue virus threat to blood safety and community health: A single center study in northern Egypt.Journal of virus eradication · 2022Article
- Full Genome Sequencing of ThreeViruses · 2022Article
- Seroepidemiologic study on convalescent sera from dengue fever patients in Jinghong, Yunnan.Virologica Sinica · 2022Article
- Prevalence of dengue NS1 antigenemia among healthy blood donors in a tertiary care hospital in Southern India.Asian journal of transfusion scienceArticle
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Authors and funding
15 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundDengue virus (DENV) infection is increasingly common in southern China and can be transmitted through blood transfusion but is not currently part of donor screening throughout the region. We assessed DENV prevalence among donors at the Xishuangbanna Blood Center, Yunnan, to support development of DENV screening strategies.
methodsBlood samples were collected randomly between June 2019 and August 2019. These were screened for anti-DENV IgG and IgM using enzyme-linked immunosorbent assay (ELISA). Then, all reactive samples and some randomly-chosen non-reactive samples were used to detect DENV RNAs using real-time polymerase-chain-reaction (RT-PCR) assays. After RT-PCR, samples were further tested for soluble nonstructural protein 1 (NS1) using the colloidal gold method. Donors demographics were also collected and assessed.
resultsOver the study period, 2254 donor samples were collected and tested for anti-DENV IgG and IgM by ELISA. This revealed 598 anti-DENV IgG and/or IgM reactive samples, a serological prevalence of 26.53%. Of these, 26 were RT-PCR positive and/or NS1 positive. Significant differences in DENV prevalence were noted by occupation (P = 0.001), education (P < 0.001), and ethnicity (P = 0.026).
conclusionThe prevalence of DENV in Xishuangbanna Blood Center was higher than most other blood centers that have implemented DENV donor screening. Our study provides first-hand data about the prevalence of DENV and allows the development of a screening strategy for clinical use.
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