Evidence map›Paper›PMID 33482692›Full record

SynthesisAutism : the international journal of research and practice2021

Intensive behavioural interventions based on applied behaviour analysis for young children with autism: An international collaborative individual participant data meta-analysis.

Mark Rodgers, Mark Simmonds, David Marshall, Robert Hodgson, Lesley A Stewart, Dheeraj Rai, Kath Wright, Esther Ben-Itzchak, Svein Eikeseth, Sigmund Eldevik and 7 more

Open access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Autism : the international journal of research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 5 countries.

Mark RodgersUniversity of York, UK.
Mark SimmondsUniversity of York, UK.
David MarshallUniversity of York, UK.ORCID 0000-0001-5969-9539
Robert HodgsonUniversity of York, UK.
Lesley A StewartUniversity of York, UK.
Dheeraj RaiUniversity of Bristol, UK.
Kath WrightUniversity of York, UK.
Esther Ben-ItzchakAriel University, Israel.
Svein EikesethOslo Metropolitan University, Norway.
Sigmund EldevikOslo Metropolitan University, Norway.
Hanna KovshoffUniversity of Southampton, UK.
Iliana MagiatiUniversity of Western Australia (UWA), Australia.
Lisa A OsborneSwansea Bay University Health Board, UK.
Phil ReedSwansea University, UK.ORCID 0000-0002-8157-0747
Giacomo VivantiDrexel University, USA.
Ditza ZachorTel Aviv University, Israel.ORCID 0000-0002-1766-2487
Ann Le CouteurNewcastle University, UK.
University of York · GBOsloMet – Oslo Metropolitan University · NOAriel University · ILDrexel University · USNewcastle University · GBSwansea Bay University Health Board · GBSwansea University · GBTel Aviv University · ILThe University of Western Australia · AUUniversity of Bristol · GBUniversity of Southampton · GB

Funding

Department of Health 16/104/15
6 · The paper itself

Abstract

lay abstractEarly intensive applied behaviour analysis-based interventions are designed to support young autistic children's learning and development. Unfortunately, the available evidence about the effectiveness of these interventions remains unclear. Several reviews have focused on the published findings rather than contacting the authors to collect and analyse data about the individual participants in the original studies. Also, most of the studies were carried out by groups involved in delivering the interventions leading to the potential bias in interpreting the results. Our research team (supported by an international advisory group) carried out an independent individual patient data review by collecting the original participant data from the authors of the studies, to examine the effectiveness of these interventions. The results suggested that early intensive applied behaviour analysis-based interventions might lead to some changes in children's cognitive ability (intelligence quotient) and everyday life skills after 2 years, compared with standard treatments. However, all the studies had problems with the way they were designed. Also, few of the studies looked at outcomes that have been described as most important to autistic people or followed children beyond 2 years. We think that further systematic reviews of the existing evidence are unlikely to add to the findings of our review. Furthermore, we recommend that future research should investigate which types of supports and interventions are most effective for children and families, prioritising outcomes measures that are meaningful for the autism community and include, wherever possible, longer-term follow-up.

Indexed as

Applied Behavior AnalysisAutism Spectrum DisorderAutistic DisorderBehavior TherapyChildChild, PreschoolEarly Intervention, EducationalHumansapplied behaviour analysisautismautism spectrum disorderindividual participant datameta-analysissystematic review

Identifiers

PMID33482692
PMCPMC8108110
OpenAlexW3123964569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.