Evidence map›Paper›PMID 33482664›Full record

ArticlePloS one2021

Domains of the autism phenotype, cognitive control, and rumination as transdiagnostic predictors of DSM-5 suicide risk.

Darren Hedley, Mirko Uljarević, Ru Ying Cai, Simon M Bury, Mark A Stokes, David W Evans

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Traumatic Experiences, Psychological Distress and Suicide-Related Behaviors in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  6. Article
  7. Lifetime stressor exposure is related to suicidality in autistic adults: A multinational study.Autism : the international journal of research and practice · 2025
    Article
  8. Article
  9. Review
  10. Occurrence and predictors of lifetime suicidality and suicidal ideation in autistic adults.Autism : the international journal of research and practice · 2024
    Article
  11. Article
  12. Employment profiles of autistic people: An 8-year longitudinal study.Autism : the international journal of research and practice · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The association between COVID-19, personal wellbeing, depression, and suicide risk factors in Australian autistic adults.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Darren HedleyOlga Tennison Autism Research Centre, La Trobe University, Melbourne, Victoria, Australia.ORCID 0000-0002-6256-7104
Mirko UljarevićUniversity of Melbourne, Melbourne, Victoria, Australia.
Ru Ying CaiAspect Research Centre for Autism Practice, Melbourne, Victoria, Australia.
Simon M BuryOlga Tennison Autism Research Centre, La Trobe University, Melbourne, Victoria, Australia.ORCID 0000-0003-1273-9091
Mark A StokesSchool of Psychology, Deakin University, Melbourne, Victoria, Australia.
David W EvansBucknell University, Lewisburg, Pennsylvania, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Suicide is a global health problem affecting both normative and clinical populations. Theoretical models that examine mechanisms underlying suicide risk across heterogeneous samples are needed. The present study explored core characteristics associated with autism spectrum disorder (ASD), a sub-population at high risk of suicide, as well as two dimensional cognitive constructs, as potential transdiagnostic predictors of suicidal ideation in a clinically diverse sample. Participants (n = 1851, 62% female) aged 18 to 89 years completed online questionnaires assessing: social communication difficulties; insistence on sameness; cognitive control; and rumination. Forty-three percent of participants reported the presence of at least one neurodevelopmental or neuropsychiatric disorder. One third of the sample reported some suicidal ideation (SI), and 40 percent met the threshold for concern for depression. All hypothesized constructs were associated with SI and depression and, with the exception of rumination, contributed significantly to SI. Participants reporting SI returned significantly higher social communication difficulties and insistence on sameness, and lower levels of cognitive control than those reporting no-SI. The study was limited by the use of a cross-sectional sample assessed with self-report measures. All diagnoses were self-reported and the study was additionally limited by the use of a single item indicator of suicidal ideation. These findings support a role for constructs associated with the ASD phenotype and associated broad cognitive domains as potential risk factors underlying suicidal ideation in a large clinically diverse sample. Our findings suggest directions for future longitudinal research studies, along with specific targets for suicide prevention and clinical practice.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersPhenotypeRumination, CognitiveAdultAgedAged, 80 and overAutistic DisorderFemaleHumansMaleMiddle AgedRiskSuicideYoung Adult

Identifiers

PMID33482664
PMCPMC7822649

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.