Evidence map›Paper›PMID 33482473›Full record

ArticleCell calcium2021

Calcineurin: A star is reborn.

Huiming Li, Patrick G Hogan

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Huiming LiProgram in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.
Patrick G HoganLa Jolla Institute for Immunology, La Jolla, CA, 92037, USA; Moores Cancer Center, University of California-San Diego, La Jolla, CA, 92093, USA. Electronic address: phogan@lji.org.
Boston Children's Hospital · USLa Jolla Institute for Immunology · US

Funding

NFAT, bZIP proteins, and transcriptional programs in lymphocytesR01AI109842 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Patrick Hogan, Anjana Rao · 2014 to 2026
$8.6M
Bioinformatic strategy to identify calcineurin interactors in the human proteomeR03AI090428 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI LI, HUIMING · 2010 to 2011
$196k
NIAID NIH HHS R01 AI109842NIAID NIH HHS R03 AI090428
6 · The paper itself

Abstract

The protein phosphatase calcineurin has long been familiar to the calcium community, but the definition of its physiological substrates has been far from complete. A new study rectifies this deficiency and sets the stage for new insights into the role of calcineurin in diverse cellular processes.

Indexed as

AnimalsCalcineurinHumansNFATC Transcription FactorsSignal TransductionSubstrate SpecificityCalcineurinNFATC Transcription FactorsCalcineurinDocking motifLxVPPhage displayPxIxITSLiMSubstrate

Identifiers

PMID33482473
PMCPMC8769354
OpenAlexW3119656196

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.