Evidence map›Paper›PMID 33482362›Full record

ArticleActa biomaterialia2021

In-vivo assessment of a tissue engineered vascular graft computationally optimized for target vessel compliance.

Kenneth J Furdella, Shinichi Higuchi, Ali Behrangzade, Kang Kim, William R Wagner, Jonathan P Vande Geest

Open access · greenAbstract read
In one paragraph

Article in Acta biomaterialia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Article
  6. A computational framework to optimize the mechanical behavior of synthetic vascular grafts.Journal of the mechanical behavior of biomedical materials · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Biomaterials science · 2023
    Article
  15. Article
  16. Article
  17. Design and computational optimization of compliance-matching aortic grafts.Frontiers in bioengineering and biotechnology · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kenneth J FurdellaDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Shinichi HiguchiMcGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Ali BehrangzadeDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Kang KimDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Mechanical Engineering and Material Science, University of Pittsburgh, Pittsburgh, PA, USA; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.
William R WagnerDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Jonathan P Vande GeestDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: jpv20@pitt.edu.
University of Pittsburgh · USMcGowan Institute for Regenerative Medicine · US

Funding

Training in Biomechanics in Regenerative MedicineT32EB003392 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WOO, SAVIO L-Y. · 2005 to 2020
$4.0M
Preclinical assessment of a compliance matched biopolymer vascular graftR56HL136517 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VANDE GEEST, JONATHAN PIETER · 2017 to 2017
$673k
NHLBI NIH HHS R56 HL136517NIBIB NIH HHS T32 EB003392
6 · The paper itself

Abstract

Tissue engineered vascular grafts (TEVGs) have the ability to be tuned to match a target vessel's compliance, diameter, wall thickness, and thereby prevent compliance mismatch. In this work, TEVG compliance was manipulated by computationally tuning its layered composition or by manipulating a crosslinking agent (genipin). In particular, these three acelluluar TEVGs were compared: a compliance matched graft (CM

Indexed as

Blood Vessel ProsthesisBlood Vessel Prosthesis ImplantationAnimalsFemaleGelatinRatsRats, Sprague-DawleyTissue EngineeringGelatinComplianceCompliance-matchedOptimizationRatTissue engineered vascular graftUltrasound

Identifiers

PMID33482362
PMCPMC7920940
OpenAlexW3123365432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.