Evidence map›Paper›PMID 33482291›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2021

The Ethics of Predicting Autism Spectrum Disorder in Infancy.

Katherine E MacDuffie, Annette M Estes, Holly L Peay, John R Pruett, Benjamin S Wilfond

Open access · greenAbstract readEditorial
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Ethical dimensions of translational developmental neuroscience research in autism.Journal of child psychology and psychiatry, and allied disciplines · 2021
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Katherine E MacDuffieUniversity of Washington, Seattle; Treuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Washington. Electronic address: kmacd@uw.edu.
Annette M EstesUniversity of Washington, Seattle.
Holly L PeayResearch Triangle Institute International, Research Triangle Park, North Carolina.
John R PruettWashington University School of Medicine, St. Louis, Missouri.
Benjamin S WilfondUniversity of Washington, Seattle; Treuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Washington.
Seattle Children's Hospital · USRTI International · USUniversity of Washington · USWashington University in St. Louis · US

Funding

Neuroethics of Predictive MRI Testing: Parental Attitudes Towards Pre-Symptomatic Identification of Autism Spectrum DisorderF32MH118689 · NIMH · UNIVERSITY OF WASHINGTON · PI MACDUFFIE, KATE E. · 2018 to 2019
$130k
NIMH NIH HHS F32 MH118689
6 · The paper itself

Abstract

Toward the end of a routine check-in appointment with your young patient-a 3-year-old boy recently diagnosed with autism spectrum disorder (ASD)-his mother shares concerns about his infant sister, currently 6 months old. The mother is aware that her daughter is at increased risk for ASD. She requests a magnetic resonance imaging (MRI) scan of her infant's brain, based on research she has read showing that MRI can be used to predict which infants will go on to develop ASD. The mother communicates that she is eager to know whether her daughter is going to develop autism so that she and her husband can prepare financially, and so she can place her daughter on the long waitlist for autism-specific services in her local community. As this family's psychiatrist, how should you respond to her request?

Indexed as

Autism Spectrum DisorderAutistic DisorderBrainChild, PreschoolFemaleHumansInfantMaleMothersSiblings

Identifiers

PMID33482291
PMCPMC8629367
OpenAlexW3122724040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.