Trans-2-enoyl-CoA reductase limits Ca

Yasunori Uchida, Yasunori Yamamoto, Toshiaki Sakisaka

Open access · goldAbstract read

In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.9field-weighted citation impact, top 32% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

A Msp1-containing complex removes orphaned proteins in the mitochondrial outer membrane ofLife science alliance · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yasunori UchidaDivision of Membrane Dynamics, Department of Physiology and Cell Biology, Kobe University School of Medicine, Kobe, Japan.

Yasunori YamamotoDivision of Membrane Dynamics, Department of Physiology and Cell Biology, Kobe University School of Medicine, Kobe, Japan.

Toshiaki SakisakaDivision of Membrane Dynamics, Department of Physiology and Cell Biology, Kobe University School of Medicine, Kobe, Japan. Electronic address: sakisaka@med.kobe-u.ac.jp.

Kobe University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endoplasmic reticulum (ER) contains various enzymes that metabolize fatty acids (FAs). Given that FAs are the components of membranes, FA metabolic enzymes might be associated with regulation of ER membrane functions. However, it remains unclear whether there is the interplay between FA metabolic enzymes and ER membrane proteins. Trans-2-enoyl-CoA reductase (TER) is an FA reductase present in the ER membrane and catalyzes the last step in the FA elongation cycle and sphingosine degradation pathway. Here we identify sarco(endo)plasmic reticulum Ca

Indexed as

Active Transport, Cell NucleusCalciumCalcium SignalingEndoplasmic ReticulumEnzyme InhibitorsFatty AcidsGene Expression Regulation, EnzymologicHEK293 CellsHumansLigandsOxidoreductases Acting on CH-CH Group DonorsProtein BindingRecombinant ProteinsSarcoplasmic Reticulum Calcium-Transporting ATPasesATP2A2 protein, humanCalciumEnzyme InhibitorsFatty AcidsLigandsOxidoreductases Acting on CH-CH Group DonorsRecombinant ProteinsSarcoplasmic Reticulum Calcium-Transporting ATPasestrans-2-enoyl-CoA reductase (NADPH)calciumcalcium ATPasecalcium transportendoplasmic reticulumfatty acid metabolismNFAT transcription factorprotein–protein interaction

Identifiers

PMID33482198

DOI10.1016/j.jbc.2021.100310

PMCPMC7949109

OpenAlexW3123324802

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.