Evidence map›Paper›PMID 33482005›Full record

ArticlePhysical therapy2021

Gait Variability and Relationships With Fear, Avoidance, and Pain in Adolescents With Chronic Pain.

Justin A Beebe, Corey Kronman, Farah Mahmud, Molly Basch, Melinda Hogan, Eileen Li, Chris Ploski, Laura E Simons

Registry-linked trialAbstract read
In one paragraph

Article in Physical therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06539247 (Comparative Effects of Motor Relearning Approach Versus Proprioceptive Neuromuscular Facilitation Technique), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06539247 nacompletednot on this mapstarted 2024, after this paper: background citation

Comparative Effects of Motor Relearning Approach Versus Proprioceptive Neuromuscular Facilitation Technique (PNF) on Pain, Foot Drop, Gait and Functional Mobility in Hemiplegic Patients

TypeinterventionalSponsorUniversity of LahoreRan2024 to 2024Enrolled68ConditionsStroke, Pain, Gait, Drop Foot, Foot DropArmsMotor Relearning Program with Electrical Muscle Stimulation (MRA + EMS), Proprioceptive Neuromuscular Facilitation Technique with Electrical Muscle Stimulation (PNF + EMS)
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Individual joint contributions to forward propulsion during treadmill walking in women with hip osteoarthritis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Justin A BeebeDepartment of Physical Therapy, Simmons University, Boston, Massachusetts, USA.
Corey KronmanDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California, USA.
Farah MahmudDepartment of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Molly BaschDepartment of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Melinda HoganDepartment of Physical and Occupational Therapy, Boston Children's Hospital, Boston, Massachusetts, USA.
Eileen LiDepartment of Physical and Occupational Therapy, Boston Children's Hospital, Boston, Massachusetts, USA.
Chris PloskiDepartment of Physical and Occupational Therapy, Boston Children's Hospital, Boston, Massachusetts, USA.
Laura E SimonsDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California, USA.

Funding

Get moving, GET living: Graded exposure treatment for adolescents with chronic musculoskeletal pain.R21AR072921 · NIAMS · STANFORD UNIVERSITY · PI SIMONS, LAURA E · 2018 to 2020
$553k
NIAMS NIH HHS R21 AR072921
6 · The paper itself

Abstract

objectiveSome children with chronic pain struggle with fear of pain, avoidance behaviors, and associated disability; however, movement adaptations in the context of chronic pain in childhood is virtually unknown. Variability in adaptive movement responses previously observed between individuals might be largely explained by the presence of problematic psychological drivers (eg, fear, avoidance). The goals of this study were to quantify the variability of gait and examine relationships among pain, fear, avoidance, function (perceived and objective), and gait variability.

methodsThis study used a cross-sectional design. Eligible patients were between 8 and 17 years of age and had musculoskeletal, neuropathic, or headache pain that was not due to acute trauma (eg, active sprain) or any specific or systemic disease. Participants completed the Numeric Pain Rating Scale, Fear of Pain Questionnaire (FOPQ), Functional Disability Inventory, and 6-Minute Walk Test and received kinematic gait analysis. Relationships were analyzed among these measures, and the self-report and functional measures were examined to determine whether they predicted gait variability (GaitSD).

resultsThe 16 participants who were evaluated (13.8 [SD = 2.2] years of age; 13 female) had high Numeric Pain Rating Scale scores (6.2 [SD = 2.1]), FOPQ-Fear scores (25.9 [SD = 12.1]), FOPQ-Avoidance scores (22.8 [SD = 10.2]), and Functional Disability Inventory scores (28.6 [SD = 9.4]) and low 6-Minute Walk Test distance (437.1 m [SD = 144.6]). Participants had greater GaitSD than age-predicted norms. Fear was related to self-selected GaitSD, and avoidance was related to both self-selected and standardized GaitSD. Avoidance predicted 43% and 47% of the variability in self-selected and standardized GaitSD, respectively.

conclusionGaitSD was significantly related to both fear of pain and avoidance behaviors, suggesting the interplay of these psychological drivers with movement. FOPQ-Avoidance was robust in accounting for GaitSD. IMPACT: This study offers preliminary evidence in understanding movement adaptations associated with adolescents with chronic pain. They may lend to more directed interventions.

Indexed as

AdolescentAdolescent BehaviorAvoidance LearningChildChronic PainCross-Sectional StudiesDisability EvaluationFearFemaleGaitHumansMalePain MeasurementPsychology, AdolescentSurveys and QuestionnairesWalk TestAvoidanceGaitGraded Exposure in VivoPain-Related FearPediatric Pain

Identifiers

PMID33482005
PMCPMC8453630

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.