Evidence map›Paper›PMID 33481314›Full record

SynthesisDermatologic therapy2021

Maculopapular skin eruptions associated with Covid-19: A systematic review.

Saad Shams, Sawai Singh Rathore, Priyanka Anvekar, Manush Sondhi, Neeraj Kancherla, Sohaib Tousif, Gianpier Alonzo Rojas, Noman Khurshid Ahmed, Mehwish Munawwar, Muhammad Noman

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Dermatologic therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Article
  6. Review
  7. [COVID-19 and skin manifestations: overview of current literature].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2022
    Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 5 countries.

Saad ShamsInternal Medicine, Ross University School of Medicine, Miramar, Florida, USA.
Sawai Singh RathoreInternal Medicine, Dr. Sampurnanand Medical College, Jodhpur, India.ORCID https://orcid.org/0000-0003-1954-094X
Priyanka AnvekarInternal Medicine, MGM Medical College and Hospital, Aurangabad, India.
Manush SondhiInternal Medicine, Kasturba Medical College, Manipal, India.ORCID https://orcid.org/0000-0002-3910-1189
Neeraj KancherlaInternal Medicine, Andhra Medical College, Visakhapatnam, India.
Sohaib TousifInternal Medicine, Ziauddin Medical University, Karachi, Pakistan.
Gianpier Alonzo RojasInternal Medicine, School of medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID https://orcid.org/0000-0002-4937-0227
Noman Khurshid AhmedInternal Medicine, Dow Medical College, Karachi, Pakistan.
Mehwish MunawwarInternal Medicine, Liaquat College of Medicine and Dentistry, Karachi, Pakistan.
Muhammad NomanInternal Medicine, Ziauddin Medical College, Karachi, Pakistan.
Ziauddin University · PKAndhra University · INCalifornia Miramar University · USDinajpur Medical College · BDDow University of Health Sciences · PKKasturba Medical College, Manipal · INLiaquat National Hospital · PKMahatma Gandhi Mission Medical College and Hospital · INUniversidad Peruana Cayetano Heredia · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this systematic review, we anticipated in summarizing clinical features, histopathological hallmarks, and possible pathology behind the maculopapular skin eruptions occurring in Covid-19 patients. A literature search was executed using MEDLINE/PubMed and Embase databases for articles published till 20 November 2020. All eligible articles including observational studies, case reports, and case series reporting the maculopapular skin lesion in Covid-19 patients were included. Data were obtained for 354 Covid-19 patients presenting with maculopapular lesions from 40 studies. The mean age of these patients was 53 years, and with 42% of them being male. These maculopapular lesions differed considerably in terms of distribution and appearance, ranging from diffuse erythematous maculopapular lesions to scattered erythematous macules coalescing into papules to maculopapular lesions in plaques. The mean duration of the lesion was 8 days. These lesions were frequently localized on trunks and extremities. Superficial perivascular dermatitis with lymphocytic infiltrate was a histopathological hallmark of these lesions. As these skin lesions may have a possible association with diagnosis, management, prognosis, and severity of the disease, all health practitioners need to be well acquainted with these Covid-19 skin lesions. Also, in the middle of this worldwide pandemic, early identification of this eruption may help manage this infection's further spread.

Indexed as

COVID-19Drug EruptionsExanthemaHumansMaleMiddle AgedPandemicsSARS-CoV-2Covid-19SARS-CoV-2skinskin diseasesviral exanthema

Identifiers

PMID33481314
PMCPMC7995033
OpenAlexW3123106797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.